Fig. 13.1 The metabolism of fluoropyrimidines (Adapted from Longley et al. [3]) For many years, the best administration schedule for FU has been debated, and many efforts have been made…
Authors No. of pts RT dose Gy/fractions/ days T2 Chemo Procedure cCR No failing Local failure Habr-Gama et al. [24] 118 50.4/28/38 Yes Bolus FUFA No surgery 32 % 8/30…
Low-risk ERC High-risk ERC Absolute factors Morphology Polypoid Ulcerated Sessile Flat raised Tumour grade G1–G2 G3–G4/signet ring Depth of invasion Haggitt 1–3 Haggitt 4 pT1sm1 pT1sm2–3 Lympho-vascular invasion No…
Fig. 6.1 Tumour cell migration within a vein (V1) and tumour cell invasion in a lymphatic vessel (L1) Independent from this, it was documented that the proportion of ‘high-risk’ tumours…
© Springer International Publishing Switzerland 2015Gunnar Baatrup (ed.)Multidisciplinary Treatment of Colorectal Cancer10.1007/978-3-319-06142-9_12 12. Introduction to Oncology Per Pfeiffer1 (1) Department of Oncology, Odense University Hospital, Sdr Boulevard 29, Odense, DK – 5000, Denmark …
Fatigue 0 None 1 Increased but not altering normal activities 2 Moderate, difficulty performing some activities 3 Severe, cannot perform some activities 4 Bedridden or disabling Nausea 0 None 1…
TNM Stage Extension to Tis N0 M0 0 Carcinoma in situ: intraepithelial or invasion of lamina propria T1 N0 M0 I Submucosa T2 N0 M0 I Muscularis propria T3 N0…
Fig. 12.1 The correct plane in total mesorectal excision TME is associated with improved local control and survival rates. The local recurrence rate following total mesenteric excision with an APR…
Fig. 14.1 Five-year overall survival by actual procedure for all patients randomized by surgeons with a lower than average conversion rate (log rank test): p = 0.013 (Wilcoxon test) (From Jayne et…
Fig. 19.1 CT 3-dimensional system to evaluate pattern of recurrence (With kind permission from Springer Science + Business Media: Höcht et al. [21], p. 110) Magnetic resonance imaging (MRI) is…
