Occult HBV Infection
Fig. 13.1 Schematic representation of the main mechanisms leading in the control of HBV activities and potentially involved in OBI occurrence. In particular, mechanisms related to host’s adaptive (functionally efficient…
Fig. 13.1 Schematic representation of the main mechanisms leading in the control of HBV activities and potentially involved in OBI occurrence. In particular, mechanisms related to host’s adaptive (functionally efficient…
Fig. 1.1 HBV DNA structure and genome organization. The inner circle represents the virion rcDNA, and the dashes represent the region of the (+) strand DNA that is yet to…
Fig. 11.1 Serological course of chronic hepatitis B virus infection. The initial immune tolerant phase is characterized by a high level of HBV replication, HBeAg positivity, and a normal ALT….
Fig. 14.1 Hepatitis B life cycle, showing nuclear and cytoplasmic stages of HBV infection and sites of action for current and future HBV treatments Two forms of RNA molecule are…
Fig. 9.1 GlobalHepatitis B Prevalence 2005 (adults 19–45 years old). Source: J.J. Ott et al./Vaccine 30 (2012) 2212–2219 About 60 % of the global population lives in areas of high…
Fig. 7.1 (a) Schematic representation of the HBV virions, HDV virions, and HBV subviral particles (SVPs). The HBV DNA genome and the HDV RNA genomes are represented as circular molecules….
© Springer International Publishing Switzerland 2016Yun-Fan Liaw and Fabien Zoulim (eds.)Hepatitis B Virus in Human DiseasesMolecular and Translational Medicine10.1007/978-3-319-22330-8_20 20. Towards HBV Eradication: Future Perspective Yun-Fan Liaw1 and Fabien Zoulim2, 3, 4 (1) Liver Research Unit, Chang…
Phase Lab characteristics Acute HBV infection – HBsAg positive <6 months, anti-HBc IgM positive – HBeAg positive, HBV DNA positive – Normal ALT or elevated ALT (symptomatic patients have usually…
Fig. 2.1 Comparison of the different in vitro and in vivo systems currently available for HBV research with respect to application and limitation In 2002 a bipotent progenitor cell line,…
© Springer International Publishing Switzerland 2016Yun-Fan Liaw and Fabien Zoulim (eds.)Hepatitis B Virus in Human DiseasesMolecular and Translational Medicine10.1007/978-3-319-22330-8_15 15. IFN-Based Therapy and Management of Patients Victor C. K. Lo1 and Harry L. A. Janssen2, 1 (1) Toronto Centre for Liver…