© Springer International Publishing AG 2017Jakub Fichna (ed.)Introduction to Gastrointestinal Diseases Vol. 110.1007/978-3-319-49016-8_9 9. Clinical Treatment in IBD Marcin Włodarczyk1, 2 and Aleksandra Sobolewska-Włodarczyk1, 3 (1) Department of Biochemistry, Faculty of Medicine, Medical University of Lodz,…
© Springer International Publishing AG 2017Jakub Fichna (ed.)Introduction to Gastrointestinal Diseases Vol. 110.1007/978-3-319-49016-8_2 2. Clinical Features of Irritable Bowel Syndrome Paula Mosińska1 and Maciej Sałaga1 (1) Department of Biochemistry, Faculty of Medicine, Medical University of Lodz,…
6.1 Dysfunction of the Intestinal Barrier Histologically, the intestinal wall has four layers: (a) mucosa, (b) submucosa, (c) muscular layer, (d) serosa. Mucosa with epithelial cells…
Fig. 8.1 Endoscopic images of pathological changes in the gastrointestinal tract in Crohn’s disease (a–c) and ulcerative colitis (d–f). Crohn’s disease: a Edematous mucous membrane with slight ulceration covered by fibrin…
Fig. 4.1 An overview on pharmacological targets for clinically validated anti-IBS drugs/interventions. ClC-2 type 2 chloride ion channels; CFTR cystic fibrosis transmembrane conductance regulator; CNS central nervous system; GC-C Guanylate cyclase…
Fig. 3.1 Bristol stool chart 3.2 Step II All the patients presenting with possible IBS symptoms should be asked if they have any of the following “red flag” indicators and should…
Signs and symptoms Crohn’s disease Ulcerative colitis Abdominal pain Often, severe Less increased Hemorrhage Seldom Very common Palpable tumor in abdomen Common Absence Fistulae Common Seldom Stenosic lesions Common Seldom…
Fig. 1 Cross section through gastrointestinal stromal tumor involving the muscularis propria and subserosa of the duodenum and involvement of mesenteric fat, with an adjacent satellite tumor nodule 1.3 Histopathology…
Fig. 1 Imaging, operative, gross, and histopathology of a liver GIST metastasis. (a) Preoperative MRI imaging of isolated peripheral liver metastasis, as noted by the arrow. (b) PET scan showing…
Site % Gastric 60–70 Small intestine 25–33 Jejunum/ileum 27 Duodenum 5 Rectum 3–10 Large intestine 3–5 Esophagus <1 Other intra-abdominal 8 Extra-abdominal <5 GIST tends to be quite friable and…
