Patient population Intervention Comparator Outcomes studied Patients with RC and SCRLM Staged rectum-first approach Liver-first approach Simultaneous resections approach Perioperative morbidity Disease free survival (DFS) OS Results Evaluation of the…
Polyp Characteristics Very large size is a relative contraindication for endoscopic removal (the skill set of the endoscopist is also a factor); polyps that involve the great majority of the…
Patient population Intervention Comparators Outcomes studied Rectal cancer patients undergoing low anterior resection with coloanal anastomosis Colonic reservoir creation: J-pouch, transverse coloplasty, or side-to-end anastomosis Straight coloanal anastomosis Postoperative morbidity…
(a) Patient population Intervention Comparator Outcomes studied Rectal cancer, post neoadjuvant chemo-radiotherapy Laparoscopically performed TME Open TME Procedure related morbidity Length of stay, complications – grade 3/4/5, anastomotic leak,…
P (patients) I (intervention) C (comparator) O (outcomes) Patients undergoing colorectal surgery 1. Laparoscopic- assisted approach or 2. Enhanced recovery program/fast track pathway 1. Traditional open surgery or 2. Conventional…
P Patient population Unresectable, metastatic colon cancer with an asymptomatic primary tumor I Intervention Primary tumor resection (colectomy) followed by 1st line chemotherapy, C Comparator 1st line chemotherapy with primary…
P (patients) I (intervention) C (comparator) O (outcomes) Patients with chronic anal fissure Surgical management Medical management Cure, recurrence, postoperative incontinence Results Lifestyle modifications consisting of sitz baths, implementing a…
Patient population Intervention Comparator Outcomes Patients’ with rectal prolapse Abdominal approach to correction of prolapse Perineal approach to correction of prolapse Recurrence of prolapse Functional outcomes Quality of life Morbidity…
Fig. 1.1 PubMed entries with keywords ‘evidence based medicine’ Without a doubt evidence-based medicine provides surgeons with a rational basis to support guidelines for treatment modalities and contributes to standardization…
Patient population Intervention Comparator Outcomes studied Patients with recurrent diverticulitis Resection Expectant management Risk of recurrence, morbidity, quality of life We performed a systematic literature search with the aim of…
