1 Etiopathogenesis Overview Heterogeneous disorders. The collective term inflammatory bowel disease (IBD) obscures the distinctive nature of Crohn’s disease and ulcerative colitis. These are separate conditions, with some overlapping and…
5 Drugs used to treat inflammatory bowel disease This chapter outlines the pharmacology, mechanism of action, indications, side effects, monitoring and contraindications of drugs currently used as specific anti-inflammatory agents…
8 Medical management of Crohn’s disease Treatment of Crohn’s disease not only depends on disease activity and site, as in ulcerative colitis, but also needs to be tailored according to…
3 Extraintestinal manifestations and complications The many systemic associations and complications of IBD affect 6–50% of patients with the disease; most affect the liver/biliary tree, joints, skin and eyes (Table…
7 Medical management of ulcerative colitis Treatment of active ulcerative colitis Treatment is determined by: • the extent of disease • the severity of the attack. Knowledge of the extent…
2 Clinical features and intestinal complications Clinical features of ulcerative colitis The onset of ulcerative colitis is usually gradual, and its natural history chronic, with relapses and remissions over many…
10 IBD in pregnancy, childhood and old age IBD can behave differently, and presents different management challenges, at different stages of life. In this chapter, we outline, in separate sections,…
6 Principles of management The management of patients with ulcerative colitis and Crohn’s disease comprises general measures, supportive treatment and specific pharmacological and surgical therapies (Table 6.1). The aims of…
