Hepatobiliary disease Ulcerative colitis Crohn disease Primary sclerosing cholangitis (PSC) ++ + Autoimmune hepatitis (AIH) ++ ++ Autoimmune sclerosing cholangitis (ASC) ++ + IgG4-associated cholangitis (IAC) ++ + Cholelithiasis −…
Urgent/emergent indications Intractable bleeding Unrelenting pain Unremitting sepsis Complications Colonic perforation Colonic stricture Elective indications Refractory to or complications of medical management Chronic malnutrition Poor growth Delayed sexual maturation Steroid…
Fig. 40.1 Proposed mechanism of pathogenesis of internal penetrating Crohn disease (Adapted from Pfefferkorn et al. [2]) Evaluation The most common presenting symptoms and signs in patients with internal penetrating…
Fig. 43.1 The natural course of postoperative Crohn’s disease Postoperative Crohn’s disease recurrence is often clinically silent. Rutgeerts and colleagues found in their initial seminal study of the natural history…
Instrument items CDAI [13] HBI [18] Clinical signs and symptoms Stools Abdominal pain General well-being No. of complications Sum of liquid/soft stools (× 2) Sum of daily score of 0–3…
Fig. 44.1 (a) Schematic drawing of constructed “J”-pouch (left) and “S”-pouch (right). (b) Normal-appearing J-pouch with efferent (top) and afferent (bottom) giving “owl’s eye” appearance. (c) Inflamed pouch with diffuse…
, Emily P. Whitfield2 , Jeremy Adler2 and Peter D. R. Higgins3 (1) Department of Internal Medicine, University of Michigan Health System, Ann Arbor, MI, USA (2) Department of Pediatrics and Communicable Diseases, Pediatric Inflammatory Bowel Disease…
Obstruction Bleeding Perforation Fistula Phlegmon Abscess Drug allergies Drug resistance Perineal disease Urologic complications Progression Growth failure Fig. 41.1 Distribution of pediatric Crohn disease (de Bie et al. [10]) Isolated…
and Manu R. Sood2, 3 (1) Children’s Hospital Medical Center, Cincinnati, OH, USA (2) Division of Pediatric Gastroenterology, Hepatology and Nutrition, Department of Pediatric, Medical College of Wisconsin, Milwaukee, WI, USA (3)…
and Justin Vandergrift2 (1) Chapel Hill, North Carolina, USA (2) Charlotte, North Carolina, USA KeywordsSelf-managementAdherencePatient activationCo-production Introduction As chronic medical conditions, such as inflammatory bowel disease (IBD), predominate as a…
