Renal Tuberculosis
(1) Urology Department, University of Turin, Turin, Italy Since 1967, renal tuberculosis has become less frequent and, as a result, surgery rare. In fact, compared to 15 years ago,…
Kidney Stones
(1) Urology Department, University of Turin, Turin, Italy Much is known regarding the frequency, prevalence, geographic manifestation, phylogenesis, etiology, physiopathology, clinical presentation, and therapy of kidney stones. Crystalline concretions…
MR Imaging in Prostate Tumor Volume Assessment: How Accurate?
Fig. 10.1 Relationship between prostate cancer volume and Gleason score (ERSPC-Rotterdam data). The columns show the number of cases (n) visualizing the percentage of Gleason score 6, 7, and 8–10…
International AS Registry: The Movember Foundation’s Global Action Plan Prostate Cancer Active Surveillance Initiative
. Since 2003, millions have joined the men’s health movement, raising in excess of AUD $730 million and funding over 1,000 projects in 21 countries focusing on prostate cancer, testicular…
Triggers for Intervention
Fig. 9.1 A schematic representation of true biological progression of the disease that can occur if initially low-grade cancer cells or histologically normal cells transform into higher-grade cancer cells However,…
Risk-Based Selection for Active Surveillance
Fig. 6.1 Definition of overdiagnosis (From Etzoioni [55]. Used with permission) Fig. 6.2 Association of different treatment strategies with life expectancy and risk of PCa progression. The downhill slope between…
Tissue-Based Markers for Risk Prediction
Company/test name Molecular type Primary endpoints Prolaris – cell cycle progression Gene expression (RNA quantification) Risk of biochemical recurrence, metastasis, and disease-specific mortality Genome DX – Decipher biopsy Gene expression (RNA quantification)…
How Should Patients on Active Surveillance Be Followed?
Risk assessment methods: frequency, timing, and triggers Study PSA test (every) DRE (every) Confirmatory biopsy (months) Repeated biopsiesa (every) Optional MRI Triggers for biopsy and/or MRI University of Toronto…
Better-Informed Decision-Making to Optimize Patient Selection
Fig. 14.1 Low-risk prostate cancer DM Patients’ Backgrounds As previous studies demonstrated [14, 15], patients have personal characteristics that may impact on the treatment DM process. Demographic, psychosocial and clinical…
Can MRI Replace Biopsy in Men on Surveillance?
Fig. 11.1 Man on active surveillance for prostate cancer (Gleason 3 + 3) diagnosed in 2010 4 cores of a TRUS standard 12-core biopsy (4 mm maximum cancer core length). The mpMRI…
