Kidney Stones

Feb 9, 2018 by in Uncategorized Comments Off on Kidney Stones

(1) Urology Department, University of Turin, Turin, Italy   Much is known regarding the frequency, prevalence, geographic manifestation, phylogenesis, etiology, physiopathology, clinical presentation, and therapy of kidney stones. Crystalline concretions…

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Triggers for Intervention

Feb 9, 2018 by in Uncategorized Comments Off on Triggers for Intervention

Fig. 9.1 A schematic representation of true biological progression of the disease that can occur if initially low-grade cancer cells or histologically normal cells transform into higher-grade cancer cells However,…

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Risk-Based Selection for Active Surveillance

Feb 9, 2018 by in Uncategorized Comments Off on Risk-Based Selection for Active Surveillance

Fig. 6.1 Definition of overdiagnosis (From Etzoioni [55]. Used with permission) Fig. 6.2 Association of different treatment strategies with life expectancy and risk of PCa progression. The downhill slope between…

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Tissue-Based Markers for Risk Prediction

Feb 9, 2018 by in Uncategorized Comments Off on Tissue-Based Markers for Risk Prediction

Company/test name Molecular type Primary endpoints Prolaris – cell cycle progression Gene expression (RNA quantification) Risk of biochemical recurrence, metastasis, and disease-specific mortality Genome DX – Decipher biopsy Gene expression (RNA quantification)…

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