Evaluation and Management of Hypertension
Abstract Hypertension is common and affects over 70 million adults in the United States. Hypertension is the major cause of cardiovascular morbidity and mortality related to stroke, heart disease, and…
Pathogenesis of Hypertension
Abstract Hypertension generally derives from a kidney mechanism of inappropriate salt retention or a neural mechanism of increased sympathetic nervous system tone. High salt intake in individuals who are salt…
Immunosuppression in Transplantation
Abstract Despite significant advances in the field of kidney transplantation resulting in decreased rates of acute rejection, there remain several areas in which the development of new drugs and therapies…
Infectious Complications of Solid Organ Transplantation
Abstract Infections remain one of the leading causes of complications following kidney transplantation. While advances in surgical techniques and modern induction and maintenance immunosuppression regimens have improved the outcomes of…
Posttransplantation Monitoring and Outcomes
Abstract In this chapter, the management of kidney transplant recipients is reviewed, beginning in the immediate postsurgical period and through the various phases following kidney transplantation. Salient issues in the…
Selection of Prospective Kidney Transplant Recipients and Donors
Abstract In this chapter, the evaluation and selection of appropriate kidney transplant recipients and living kidney donors are reviewed. For recipient selection, important issues in the medical evaluation, such as…
Outcomes of Kidney Replacement Therapies
Abstract Individuals with kidney failure have multiple different options for further treatment. In addition to conservative care, discussed elsewhere, major kidney replacement therapy options include hemodialysis, peritoneal dialysis and kidney…
Hemodialysis and Hemofiltration
Abstract Hemodialysis is a form of extracorporeal kidney replacement therapy for patients with end-stage renal disease. Successful delivery hemodialysis requires a knowledge of the mechanisms involved in solute clearance and…
Peritoneal Dialysis
Abstract Peritoneal dialysis (PD) is an important kidney replacement therapy option and is often the modality of first choice in a patient’s journey through end-stage kidney failure. PD relies on…
Anemia and Other Hematologic Complications of Chronic Kidney Disease
Abstract The prevalence of anemia in patients with chronic kidney disease (CKD) increases with CKD severity from 20% to 40% in stage 3 to greater than 70% in stage 5….
