Abstract Earlier chapters in this book describe how ablative therapies have essentially replaced surgery for the management of Barrett’s esophagus (BE) with high-grade dysplasia. However, resectional therapies, performed either with…
Abstract This chapter focuses on historical trends of endoscopic ablation of Barrett’s esophagus (BE) and intramucosal esophageal adenocarcinoma (EA). Background is provided with regard to endoscopic management using ablative therapies…
Abstract Endoscopic cryospray ablation or cryotherapy is a unique method of ablation that offers a versatile choice in the treatment of Barrett’s and early esophageal cancer. Cryotherapy is performed with…
Abstract Radiofrequency ablation (RFA) is an endoscopic treatment modality for Barrett’s esophagus (BE), which has proven to be effective in eradicating Barrett’s mucosa and associated dysplasia without the known drawbacks…
Abstract Barrett’s esophagus (BE) is an acquired disorder in which metaplastic columnar epithelium replaces the stratified squamous epithelium that normally lines the lower part of the esophagus. The disorder develops…
Abstract Optical coherence tomography (OCT) is an optical analog of ultrasound imaging that was invented in the early 1990s. OCT fills a resolution gap between confocal laser endomicroscopy (CLE) and…
Abstract Confocal laser endomicroscopy (CLE) provides real-time microscopic imaging within the esophagus after administration of fluorescein. It permits immediate diagnosis of Barrett’s esophagus and associated intraepithelial neoplasia (dysplasia). Multiple trials…
Abstract The incidence of adenocarcinoma of the esophagus is increasing more rapidly than any other type of carcinoma in the United States. Almost 100% of cases occur in patients with…
Abstract It has been estimated that 5.6% of adults in the United States have Barrett’s esophagus (BE). The metaplastic columnar mucosa of BE can silently evolve into adenocarcinoma and thus…
Abstract Barrett’s esophagus is a condition in which normal stratified squamous epithelium of the esophagus is replaced with columnar epithelium. It is the primary precursor lesion for esophageal adenocarcinoma and…
