There is little debate that monoclonal antibodies directed against tumor necrosis factor-α (anti-TNFα) represent important tools in our armamentarium in the management of inflammatory bowel disease (IBD). However, the beneficial…
Randomized controlled trials support the use of the thiopurines and anti-tumor necrosis factor α (anti-TNF) monoclonal antibodies (mAb’s) in the treatment of Crohn disease (CD). Nonetheless, lack of response, loss…
Introduction and Classification of Complications of Ileal Pouch Approximately 20% to 30% of patients with ulcerative colitis (UC) eventually require surgery for failure of medical therapy or development of neoplasia….
Perianal fistula, defined as an abnormal communication between the anal canal or lower rectum and the perianal or perineal skin, is among the more morbid manifestations of Crohn disease (CD)….
Clostridium difficile is a Gram-positive anaerobe described as early as 1935 as being a member of the intestinal flora in neonates. It was not until 1978 that it was first…
Recent data suggest that inflammatory bowel disease (IBD) patients do not receive preventive services with the same rigor as other medical patients, partly because their gastroenterologist is often the main…
Inflammatory bowel disease (IBD) is a generic term used to describe Crohn disease (CD), ulcerative colitis (UC) or IBD type unclassified (IBDU), formerly known as indeterminate colitis. By definition, only…
Crohn disease is a chronic inflammatory condition, affecting the entire gastrointestinal tract, that follows a relapsing and remitting course. Approximately two-thirds of patients with Crohn disease undergo a resective surgery…
Patients with longstanding, extensive ulcerative colitis are at increased risk of developing colorectal cancer. The risk is lower than previously reported, but colonoscopic surveillance is recommended still to detect intraepithelial…
Endoscopy plays an essential role in the diagnosis, management, and surveillance of inflammatory bowel disease (IBD). Endoscopy in combination with clinical findings, blood tests, and stool analysis can help establish…
