Disorders of Extracellular Fluid Volume: Basic Concepts

Jun 20, 2017 by in NEPHROLOGY Comments Off on Disorders of Extracellular Fluid Volume: Basic Concepts

Afferent mechanisms Efferent mechanisms High pressure (arterial) volume receptors Glomerular filtration rate Carotid sinus Peritubular capillary Starling forces Aortic arch Tubular luminal composition Intrathoracic low pressure (venous) receptors Medullary blood…

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Disorders of Potassium: Hypokalemia

Jun 20, 2017 by in NEPHROLOGY Comments Off on Disorders of Potassium: Hypokalemia

Cause Mechanism 1. Dietary Low K+ diet Combination of low dietary K+ and its obligatory loss in urine Eating disorders Low oral intake and total body K+ depletion High carbohydrate…

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Intravenous Fluids: Composition and Indications

Jun 20, 2017 by in NEPHROLOGY Comments Off on Intravenous Fluids: Composition and Indications

Crystalloids Colloids Dextrose in water (D5W) (2.5 %, 5 %, 10 %) Albumin (5 %, 25 %) Sodium chloride (NaCl) (0.225 %, 0.33 %, 0.45 %, 0.9 %, 3 %, 5 %, 7.5 %) Starches (Hetastarch 5 %, Pentastarch 10 %) Ringer’s lactate Dextrans…

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Disorders of ECF Volume: Nephrotic Syndrome

Jun 20, 2017 by in NEPHROLOGY Comments Off on Disorders of ECF Volume: Nephrotic Syndrome

Fig. 9.1 Mechanisms of renal Na+ and water retention and edema formation in nephrotic syndrome Experimental evidence also suggests that Na+ and water retention occur in the kidney due to…

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Disorders of ECF Volume: Cirrhosis of the Liver

Jun 20, 2017 by in NEPHROLOGY Comments Off on Disorders of ECF Volume: Cirrhosis of the Liver

Fig. 8.1 Mechanisms of renal Na+ and water retention and edema formation in cirrhosis. EABV effective arterial blood volume, ADH antidiuretic hormone, ANP atrial natriuretic peptide, AII angiotensin II Clinical…

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Diuretics

Jun 20, 2017 by in NEPHROLOGY Comments Off on Diuretics

Group Chemical nature Prototype drug(s) Site of action Mechanism of action Relative natriuretic potency Osmotic diuretics Polysaccharide Mannitol Predominantly proximal tubule and loop of Henle Inhibition of tubular reabsoption of…

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Types of Closure

Jun 13, 2017 by in ABDOMINAL MEDICINE Comments Off on Types of Closure

Fig. 4.1 Barker Vac Pack Scissors are used to create fenestrations in the 10 × 10 drape to allow for outward egress of fluids. The Steri-Drape is then placed circumferentially under the…

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The Biologics Explosion Era

Jun 13, 2017 by in ABDOMINAL MEDICINE Comments Off on The Biologics Explosion Era

Product Source Cross-linked Sterilization method Alloderm (Lifecell, Branchburg, NJ) Human dermis No Ionic Allomax (Davol, Warwick, RI) Human dermis No E beam Flex HD (Ethicon, Sommerville, NJ) Human dermis No…

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