Immunosuppressive agent Interacting agent Effect of interacting agent Recommendations/monitoring Calcineurin inhibitors Antifungals Anidulafungin No significant effect Amphotericin B Increased risk of nephrotoxicity Appropriate hydration; monitor renal function closely Caspofungin…
1 year 5 years 10 years SPK 0.039 0.161 0.329 PAK 0.178 0.462 0.577 PTA 0.198 0.460 0.605 Data is from the SRTR 2011 Annual Report. 1-year data is…
A B Age 60 or older 50–59 and two of the following characteristics Creatinine >1.5 mg/dL Hypertension History of hypertension Cause of donor death Cerebrovascular death ECD donors are…
Screening test Sensitivity (%) Specificity (%) PPV (%) NPV (%) BK viremiaa 100 96 50 100 BK viruriab 100 92 31 100 Decoy cellsc 25 84 5 97 Urinary capsid…
Acute tubular necrosis Urological/surgical complications • Urinary leak • Lymphocele • Ureteral obstruction • Catheter obstruction • Bleeding/hematoma Vascular causes • Hypovolemia/hypoperfusion • CNI toxicity (vasoconstriction) • Thrombosis of the…
Modifiable risk factors 1. Smoking 2. Sun exposure 3. Geographical location 4. Immunosuppressive drug therapy Non–modifiable risk factors 1. Age 2. Male gender 3. White ethnicity 4. Genetic disposition 5….
Study n Age (years) Cholesterol > 200 mg/dL (%) LDL > 100 mg/dL (%) HDL < 40 mg/dL (%) TG mean (mg/dL) Moore et al. [26] 214 44.7 90 97 48 195 Aakhus et al. [27]…
Matthew R. Weir and Edgar V. Lerma (eds.)Kidney Transplantation2014Practical Guide to Management10.1007/978-1-4939-0342-9_17 © Springer Science+Business Media New York 2014 17. Risks of Pregnancy in Renal Transplant Recipients Dianne B. McKay1 and Michelle A. Josephson2 (1) Department of Medicine-Nephrology, University…
Matthew R. Weir and Edgar V. Lerma (eds.)Kidney Transplantation2014Practical Guide to Management10.1007/978-1-4939-0342-9_16 © Springer Science+Business Media New York 2014 16. Psychosocial Issues in Renal Transplantation Charles Cangro1 (1) University of Maryland School of Medicine, 22 S….
Fig. 5.1 University of Maryland alloantibody removal protocol for live donor kidney recipients who have a positive crossmatch with their donor Fig. 5.2 Graft survival in positive crossmatch cases compared…
