Pharmacotherapy in Treatment of Obesity
Common disease states in gastroenterology are more effectively treated in an obese patient when weight loss is incorporated into the treatment plan. Strategies that seek to achieve weight loss improve…
The Gut Microbiota
Obesity is an emerging global epidemic with profound challenges to world health care economies and societies. Traditional approaches to fighting obesity have not shown promise in promoting a decline in…
Obesity Epidemiology Worldwide
Obesity continues to be a public health concern across the globe. Obesity has a demonstrated association with health behaviors and health outcomes, such as diabetes, hypertension, and cancer. Over the…
Physiologic and Neural Controls of Eating
Multiple physiologic and neural systems contribute to the controls over what and how much we eat. These systems include signaling involved in the detection and signaling of nutrient availability, signals…
Obesity and Gastroenterology
Octavia Pickett-Blakely, MD, MHS, Editor Linda A. Lee, MD, Editor Overweight and obesity have emerged as major threats to public health all over the world. The 2013 Burden of Disease…
Basic Definitions and Concepts: Organization of the Gut Microbiome
New claims are frequently made for a role for the microbiome in a disease or disorder previously considered remote from the gut. The microbiome has been linked to such seemingly…
Biology of the Microbiome 1
The intestinal immune system is intimately connected with the vast diversity of microbes present within the gut and the diversity of food components that are consumed daily. The discovery of…
The Gut Microbiome in Irritable Bowel Syndrome and Other Functional Bowel Disorders
Emerging data from epidemiologic, microbiome, and physiology research in patients with functional bowel disorders (FBDs) provide evidence for a linkage between alterations in the intestinal microbiota and FBDs. However, currently…
The Gut Microbiota in Inflammatory Bowel Disease
Genes, bacteria, and immunity contribute to the pathogenesis of inflammatory bowel disease. Most genetic risk relates to defective sensing of microbes and their metabolites or defective regulation of the host…
Gut Microbiota and Complications of Liver Disease
Chronic liver disease, cirrhosis, and its complications are epidemic worldwide. Most complications are mediated through a dysfunctional gut-liver axis. New techniques have made culture-independent analysis of the gut microbiome widespread….
