Abdominal Key

Overall Bottom Line Despite landmark advances in surgical techniques and immunosuppression, PNF following LT remains a major cause of early graft and patient loss. Though not fully elucidated, the etiology…

Overall Bottom Line Diagnosis of ALF in children is more complex than in adults, as encephalopathy may be subtle, appear late and may even remain unrecognized. History is usually taken…

Overall Bottom Line A unique feature of the liver is its dual blood supply via the hepatic artery and portal vein. LT requires a minimum of three, and very frequently…

Overall Bottom Line Cirrhosis is the most common cause of portal hypertension. Causes of NCPH include hepatovenous or portomesenteric thrombosis, alcoholic hepatitis and sinusoidal obstruction syndrome. Atypical patterns of intrahepatic…

Overall Bottom Line From a clinical perspective it is very important to distinguish between “histological” and “clinically relevant” AR. The majority of AR episodes occur in the first 6 weeks…

Overall Bottom Line Improvements in organ selection, procurement and preservation have dramatically reduced the incidence of biliary complications after LT. Despite standardization of surgical methods in biliary reconstruction, immunosuppression, and…

Overall Bottom Line Autoimmune liver conditions such as AIH, PBC and PSC all recur post-LT but graft loss is uncommon. Patients with HBV do extremely well post-LT because of the…

Overall Bottom Line The most frequent CR is preceded by one or more episodes of AR that are often resistant to corticosteroid therapy and require anti-lymphocyte or other rescue therapy….

Overall Bottom Line The prevention of bacterial, fungal and viral infections after LT is essential to successful outcomes. Early recognition of infection is essential for implementing the appropriate treatment strategy…

Overall Bottom Line Patients with underlying acute and chronic liver disease are at risk of morbidity and mortality after surgery. The magnitude of the risk is related to the severity…