Transduodenal Resection of Ampullary Tumor: Pancreaspreserving Duodenal Resection



Transduodenal Resection of Ampullary Tumor: Pancreaspreserving Duodenal Resection


Kristy L. Rialon

Theodore N. Pappas





PREOPERATIVE PLANNING


Laboratory Values

Serum bilirubin, alkaline phosphatase, transaminases, and pancreatic enzymes should be checked as these can be elevated in cases of biliary obstruction and pancreatitis. The prothrombin time may be elevated secondary to malabsorption of vitamin K. Those who present with bleeding need to be followed with serial hematocrits and hemoglobins.



Imaging

The presentation of symptoms described above leads to further evaluation by abdominal ultrasonography (US), computed tomography (CT), endoscopic ultrasound (EUS), magnetic resonance cholangiopancreatography (MRCP), and endoscopic retrograde cholangiopancreatography (ERCP). On ultrasound, the lesion is seen as a lump echo in the ampullary region of the common bile duct and there may be distention of the intrahepatic and extrahepatic ducts. CT is a common imaging modality that is useful in detection of diseases of the abdominal cavity and will show ductal dilatation and hepatic metastases, but can miss small tumors.

Prior to both operations, one must obtain either EUS, MRCP, or ERCP to be certain the tumors are not growing through the duodenal wall (which would suggest invasive disease), to determine the location of the minor ampulla, and to know if divisum anatomy is present. EUS provides high-resolution images of the duodenum, ampulla, bile and pancreatic duct walls, pancreatic head, local lymph nodes, and neighboring blood vessels. Tumor extension into the wall of the duodenum or head of the pancreas, as well as lymph node involvement, can be demonstrated by EUS. However, EUS cannot differentiate early malignant tumors from benign ones and inflammatory lymph nodes from malignant ones, demonstrate distant metastases, or identify the margins of large tumors, due to its 2 to 4 cm depth of view.

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Jun 15, 2016 | Posted by in HEPATOPANCREATOBILIARY | Comments Off on Transduodenal Resection of Ampullary Tumor: Pancreaspreserving Duodenal Resection

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