Obliterative Procedures



Obliterative Procedures


Thomas L. Wheeler II

Holly E. Richter



INTRODUCTION

The elderly population, especially 85 years or older, is experiencing an increasing rate of growth (1). As a result, the number of patients presenting for treatment of pelvic organ prolapse, including those who do not desire to maintain sexual function, is also increasing (2,3). Many of these patients will not be sexually active for a variety of reasons and restorative reconstructive surgery may not be desired. For these patients, the pelvic reconstructive surgeon should be comfortable discussing the option of obliterative vaginal procedures. Shorter operative time and less surgical risk are the advantages of this approach over traditional vaginal reconstructive procedures (4). The obliterative procedures for severe prolapse are total colpocleisis (i.e., colpectomy) and partial colpocleisis, with or without levator myorrhaphy and high perineorrhaphy. When a colpocleisis is not technically feasible, a constricting anterior and posterior colporrhaphy with levator myorrhaphy and high perineorrhaphy may be considered.

Partial colpocleisis approximates denuded portions of the anterior and posterior vagina; therefore, the uterus may be left in place as lateral channels are formed from which cervical drainage or blood can escape. Since a total colpocleisis involves complete denudation and does not leave drainage channels, concurrent or previous hysterectomy is necessary. Either way, potential colpocleisis candidates should be counseled regarding the loss of a sexually functioning vagina.


HISTORY

Throughout history, women have endured severe pelvic organ prolapse. Ineffective methods of correction that were attempted included vaginal packing, crude pessaries, and instillation of caustic materials. Some women were even hung upside down to invert the prolapse back into the pelvis (5). Initial attempts at surgical management involved amputation of the prolapsing segments or closure of the vaginal introitus (6), with unsatisfactory results.

The idea to surgically obliterate severe prolapse is credited to Gerardin, who suggested suturing surgically denuded anterior and posterior vaginal walls together (7). Even though he wrote about this technique in 1823, he never attempted the procedure. Subsequently, the first known procedure was performed in 1867 by Neugebauer, who waited until 1881 to publish his technique (8). Neugebauer obliterated the vagina by denuding 6 × 3-cm anterior and posterior areas near the introitus and suturing them together. Leon Le Fort’s technique was actually published first in 1877 (9). Le Fort’s modifications differed in that longer and narrower areas of denudation were performed and that a colpoperineoplasty was performed 8 days after the colpocleisis to address the widened genital hiatus. In general, a partial colpocleisis is referred to as a Le Fort colpocleisis, but a less common eponym is the Neugebauer-Le Fort procedure. Edebohls, in 1901, was the first to report performing a total colpocleisis with levator myorrhaphy following hysterectomy (i.e., panhysterocolpectomy) (10,11). His report was followed by several case series that had comparable results to the partial colpocleisis-type procedures (12). Even though adoption of the colpocleisis procedure was slow in the United States, in 1880, Berlin reported three cases (one of which failed) to the New England Hospital (13). This failure was blamed on lack of a concurrent perineorrhaphy being performed.

In the attempt to make colpocleisis more acceptable, early modifications were directed at reducing the risk of recurrence or the incidence of postoperative urinary incontinence, which was as high as 25% (14) and attributed to scarring from a
distal dissection and pulling down of the bladder neck. An early example to increase the robustness of the repair was creating a wider septum, as reported by Wyatt in 1912 (15). Other authors addressed postoperative urinary incontinence by sparing the distal vagina near the urethra or by supporting the bladder neck with a high perineorrhaphy (6,15, 16, 17, 18, 19). Goodall and Power in 1937 tried to preserve sexual function by creating a triangular septum higher in the vagina that would allow for intercourse and potentially less stress urinary incontinence (20).


PATIENT SELECTION AND CONSIDERATIONS

The classic example of a candidate for colpocleisis is an older, sexually inactive patient who has medical comorbidities that make a quick and relatively noninvasive procedure attractive. Further, she has either declined pessary or had unsatisfactory results. Sometimes this description includes patients who may have a spouse. Therefore, the patient and her partner need to be counseled that intercourse is not possible after colpocleisis, even if her quality of life improves. Candidates should also be counseled that reported satisfaction rates are greater than 85% and regret rates are less than 11% (19,21, 22, 23, 24).


Urinary Incontinence

Another consideration when evaluating potential candidates for an obliterative procedure is postoperative urinary incontinence. Initially, the occurrence of postoperative urinary incontinence, up to 25% (14), was probably the biggest deterrent against the performance of the procedure. In fact, early in the development of colpocleisis, some surgeons did not address urinary incontinence if it existed preoperatively. De novo stress incontinence has been attributed to (a) distal vaginal dissection with scarring and resultant downward traction on the urethra and (b) unmasking of occult stress urinary incontinence by reducing the prolapse, which previously had “kinked” the bladder neck.

To minimize this problem, contemporary colpocleisis techniques avoid distal dissections that predispose to downward traction on the urethra and include incontinence procedures for appropriately selected patients (14,16,17,25).

The decision to perform an incontinence procedure in these patients is difficult and should be individualized. Patients should be evaluated for urinary incontinence and bladder function because the morbidity of postoperative stress incontinence against the possibility of urinary retention must be considered. Unfortunately, there are mixed results on the impact of colpocleisis on bladder emptying (14,26). If no voiding dysfunction is suspected, candidates should be evaluated at least with simple cystometrics with reduction of the prolapse and measurement of a postvoid residual. Otherwise, urodynamic evaluation is warranted, even though complex urodynamics have not been shown to be sensitive in distinguishing if the cause of poor bladder emptying is due to, for instance, severe prolapse or detrusor motor impairment.

In addition to bladder testing, the surgeon must also judge the patient’s ability to perform self-catheterization, because decreased manual dexterity is common in these patients. All patients, whether or not an incontinence procedure is performed, should be counseled on the possible need for prolonged bladder drainage with indwelling Foley or intermittent catheterization. As a compromise between highly effective stress incontinence procedures that may increase urinary retention rates versus no procedure, a Kelly plication procedure can be considered.


Management of the Geriatric Patient

Advanced age alone is not a contraindication to any type of surgery, including colpocleisis. However, surgeons who perform colpocleisis need to be adept at surgical care of the geriatric patient.

In addition to open communication with the anesthesiologist regarding the optimal method of anesthesia, cardiac, pulmonary, nutritional, cognitive, and functional status may need to be accounted for preoperatively. The goal is to minimize risk factors for the occurrence of complications. From a cardiac standpoint, a diastolic blood pressure greater than 110 mm Hg should postpone surgery. Many antihypertensives should be given the day of surgery and restarted immediately after surgery, as the risk of severe hypertension greatly outweighs the risk posed by giving medicine prior to anesthesia induction. Consultation with an internist or cardiologist should be considered for patients on multiple classes of antihypertensive medications. Poor functional status, as shown by decreased activities of daily living (ADL), is predictive of pulmonary complications and should prompt a rigorous preoperative assessment (27).

Postoperative delirium may be seen in up to 10% of older surgical patients and is often misdiagnosed, leading to longer hospital stays, nursing home admits, and morbidity. Baseline dementia increases the incidence of acute postoperative delirium
and adverse outcomes. A basic check of cognitive function should be performed in older surgical candidates, and if cognitive processes are impaired, consultation with an internist, geriatrician, neurologist, or other individual skilled in dementia management should be considered perioperatively to reduce the risk of postoperative delirium. Poor nutrition inhibits wound healing, and a serum albumin may be checked to assess preoperative nutritional status (27). A history of alcohol abuse should be elicited, and smoking should be stopped. Routine laboratory studies include hematocrit, electrolytes, blood urea nitrogen, and creatinine, while other studies to be considered are complete blood cell count, platelets, arterial blood gases, and prothrombin time and partial thromboplastin time (27).

Perioperative and postoperative care are tailored for a speedy recovery and avoidance of a decline in functional status. After colpocleisis, early ambulation is vital. Hypertensive episodes can be managed by identifying an underlying cause such as pain or lack of medications. Potent direct vasodilators are contraindicated because of the potential exacerbation of diastolic dysfunction commonly found in the elderly; therefore, volume overload should be avoided. Adequate pain control must be ensured, along with avoidance of common drug-drug interactions in this population. Atelectasis is a common postoperative occurrence; therefore, incentive spirometry should be initiated immediately after surgery with turning, coughing, and deep breathing to prevent increased respiratory compromise. Delirium occurrence is reduced by improving orientation, decreasing sensory overload or deprivation, and providing reassurance. Prophylaxis should also be employed against deep venous thrombosis, infection, and constipation (27).


Concurrent Hysterectomy

In general, hysterectomy should be reserved for pathologic indications or if a total colpocleisis is planned. The main benefit of routine hysterectomy would be the prevention of endometrial or cervical cancer, in addition to the rare event of pyometra after partial colpocleisis secondary to blocked lateral channels (28). The main argument against routine hysterectomy is that the advantages of less operative time and a less invasive technique with partial colpocleisis are compromised. Two observational studies showed longer operating times, with one of these studies showing increased blood loss and a longer hospital stay (22,26). Von Pechmann reported two cases of conversion to exploratory laparotomy in the hysterectomy group (22). If hysterectomy is not performed, a Pap smear, if indicated, and endometrial assessment with ultrasound or sampling should be considered. A dilatation and curettage may be performed as clinically indicated.


Perineorrhaphy and Levator Myorrhaphy

The rationale behind performing this concurrent procedure is to narrow the introitus and create a platform whereby less gravitational tension is placed on the colpocleisis procedure. In theory, this platform may reduce the risk of anatomical failure and downward tension on the urethra, a proposed etiology of postoperative stress incontinence. This procedure is encouraged, especially for candidates who are physically active. Formal study of the role of perineorrhaphy and levator myorrhaphy is probably unlikely due to the high success noted with this concurrent procedure.


TECHNIQUES


Partial Colpocleisis

The cervix or vaginal vault is grasped and brought out through the introitus. A marking pen is used to outline two rectangular areas on the vaginal wall for incision, one on the anterior vaginal wall and one on the posterior wall (Fig. 31.1). When the cervix is present, the incision borders closest to the cervix are demarcated approximately 0.5 cm from the cervical vaginal reflection. The border of the rectangle closest to the bladder neck is placed approximately 2 cm from the urethrovesical junction in order to allow for minimal traction on the bladder neck area. The sides of the rectangle are demarcated lateral to any cystocele defect that is present. In cases of vaginal vault prolapse, the rectangles begin approximately 1 cm anterior and posterior to the cuff. The inferior border of the posterior rectangle is at least 2 cm inside the hymenal ring. The lateral lines should leave approximately 2 cm between the anterior rectangle and posterior rectangle.

The outlined epithelium can be infiltrated with saline or vasoconstrictor of choice. It is then incised and removed off the underlying rectum and enterocele posteriorly and bladder anteriorly. Sharp dissection is performed to leave as much musculoconnective tissue overlying these structures as is possible while maintaining an avascular plane of dissection (Fig. 31.2). The enterocele is not entered. This dissection can be performed with electrocautery, which may decrease blood loss.

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Jul 24, 2016 | Posted by in UROLOGY | Comments Off on Obliterative Procedures

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