Finally, early orchidopexy is recommended in all patients because it often allows them to achieve normal production of sex hormones at puberty. In addition, it greatly facilitates a regular examination for testicular malignancies.

The prognosis of patients with PBS who survive the postnatal period depends primarily on the severity and progression of renal dysfunction. Unfortunately, even those who survive infancy with mild renal impairment may progress to renal failure due to recurrent pyelonephritis, particularly in patients who incompletely empty their bladders. Renal transplantation has been shown to be a feasible option for these patients.