At present, no directed treatment is available to prevent or slow further cyst formation, although several experimental therapies are being studied. Instead, treatment is chiefly directed at reducing the morbidity associated with complications of the renal cysts, such as pain, hemorrhage, infection, and hypertension. If pain becomes severe, some centers offer laparoscopic unroofing of cysts or percutaneous aspiration of cyst fluid and injection of sclerosing material. Hepatic cysts are usually asymptomatic, but in rare cases portal hypertension may occur. About 10% of those with ADPKD and intracranial aneurysms will die of subarachnoid hemorrhage; however, screening for intracranial aneurysms is generally not performed unless there is a family history of aneurysm rupture, the patient has a high-risk occupation (e.g., pilot), or there are concerning neurologic symptoms.