Diversion type
Advantages
Disadvantages
All diversions
Drain kidneys effectively
Made out of own bowel tissue
Mucous in urine
Most are colonized with bacteria
Risk of symptomatic infections
Risk of kidney stones
Ureteral strictures
Metabolic complications
Ileal conduit
Simplest, quickest to perform
Familiar to most surgeons
Easiest for others to care for
Only option if kidney function is poor
Must wear a bag on skin at all times
High risk of parastomal hernia
Problems with appliance fit, urine leak, skin irritation
Stomal stenosis
Orthotopic neobladder
Only slightly longer surgery than conduit
Void per urethra, most “natural”
No external appliance or stoma
Initial significant incontinence, may not resolve
Nighttime incontinence common long-term
Most patients wear pads at least some of the time
May require self-catheterization (men 10%, women >50%)
Neobladder stones (uncommon)
Continent cutaneous diversion “Indiana pouch”
Dry immediately
May be able to sleep through night
No external appliance
Significantly longer surgery
Have to catheterize to empty
Risk of stoma problems – difficulty catheterizing or leak, about 20%
Many urologists and ER physicians don’t know how to manage complications
Stones in reservoir
Second, patients and their families need help to identify their own priorities and tolerance for the disadvantage of each type of diversion. This is an iterative process as they understand the pros and cons and try to prioritize those for themselves. This may require several discussions over time. Providing written materials, encouraging patients to talk to others who have been through the various procedures, and encouraging open family discussions are all helpful. It is also useful to have a trained physician extender who can help answering specific questions and guide the patient through the process.
Finally, it is important that we physicians recognize how much our own bias can influence the decision. Physicians are trained to be persuasive, and it is relatively easy to influence patients’ decisions just based on how the options are presented to them and the inflections of the advice delivered. There are marked differences in the rate of continent diversion at various institutions, even at those with specialists who have extensive experience in continent diversion [33]. Nationally less than 20% of patients undergo continent diversion, compared to 60–75% at some high-volume centers [34]. One center reported a marked decrease in continent diversion over a 5-year timespan, almost certainly reflecting physician bias rather than any radical difference in their patient population [35]. Many urologists today have had little exposure to continent diversion in training or after and may not want to refer the patient out to a center where that option may be offered [36]. There is also a significant financial disincentive for surgeons to perform a procedure that takes extra time when there is not a concomitant increase in reimbursement [37].
Conclusions
Continent urinary diversion is not new or experimental and should be considered as a potential option for each patient undergoing cystectomy and urinary diversion. There are few absolute contraindications which only exclude a minority of patients undergoing cystectomy today. The ultimate decision about the best diversion for a specific patient requires consideration of both cancer-related and patient-related factors and requires truly shared decision-making between patients, their physicians, and their families.
References
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Winters B, Cai J, Daneshmand S. Short-term change in renal function in patients undergoing continent versus non-continent urinary diversions. UroToday Int J. 2013;6(2):art 20.
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Eisenberg MS, Thompson RH, Frank I, et al. Long-term renal function outcomes after radical cystectomy. J Urol. 2014;191(3):619–25.CrossRefPubMed