© Springer-Verlag London 2017Abhay Rané, Burak Turna, Riccardo Autorino and Jens J. Rassweiler (eds.)Practical Tips in Urology10.1007/978-1-4471-4348-2_19
19. Management of Severe Hemorrhagic Cystitis
Department of Urology, “Victor Babes” University of Medicine and Pharmacy, Timisoara, Romania
Hemorrhagic cystitis is a significant urological condition, consisting of inflammation and/or damage of the urinary bladder mucosa and superficial blood vessels, with subsequent diffuse bleeding. It can present with main clinical symptoms and a number of possible causes have been identified. Treatment options, from general supportive measures to surgical procedures, for this challenging disease are described in this chapter.
Hemorrhagic cystitis is a significant urological condition, consisting of inflammation and/or damage of the urinary bladder mucosa and superficial blood vessels, with subsequent diffuse bleeding. Its main clinical symptoms are: persistent (and frequently severe) hematuria, urinary frequency, suprapubic pain, and even acute urinary retention (due to blood clots). A large number of possible causes of hemorrhagic cystitis have been identified, including radiation therapy (for prostate or cervical cancer), infectious pathogens (viral, as BK virus, adenovirus, herpes virus, or bacterial, as Escherichia Coli, Proteus Mirabilis, or Klebsiella), and chemical or drug exposure (to cyclophosphamide, ifosfamide, busulfan, thiotepa, or aniline dye, among many others).
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