Ligation of the Intersphincteric Fistula Tract (LIFT)
Husein Moloo
Joshua I. S. Bleier
Stanley M. Goldberg
Introduction
The treatment of fistula-in-ano is difficult and there are a variety of treatment options. To approach fistula repair in a systematic manner, the anatomy must be accurately understood; Parks provides a useful anatomic classification (1). In addition, in a separate paper, he described patients who have fistulas whose treatment place them at higher risk of developing impairment of continence (2)—the term “complex” fistula is based on a modification of Parks classification (3).
Complex fistulas are defined as those that traverse >30% of the external sphincter (high transsphincteric, suprasphincteric, and extrasphincteric fistulas according to Parks (2)), are anterior in a female, have multiple tracks, are recurrent, in patients with pre-existing continence issues, irradiation, or Crohn’s (3).
Historically, approaches to these fistulas were quite varied. Lay-open fistulotomy, while successful, results in incontinence due to destruction of significant portions of the sphincter complex. Sphincter-sparing approaches such as advancement flaps and core-out fistulectomies were morbid and have varying success. Current methods to treat these fistulas include the fistula plug, fibrin glue, cutting seton, and advancement flaps with varying rates of success and impact on continence (4,5,6,7,8,9). There is no consensus on the best approach to this difficult problem (3).
Indications/Contraindications
The ligation of the intersphincteric fistula tract (LIFT) is a promising new sphincter-sparing procedure first described by Rojanasakul et al. in 2007 (10). The main concept in the LIFT procedure is identification of the intersphincteric fistula tract (in the intersphincteric groove) with its subsequent ligation. There is no division of the sphincter muscle, and theoretically, continence should be preserved. This technique has been
used on low and high trans-sphincteric fistulas as well as suprasphincteric and extrasphincteric fistulas (10).
used on low and high trans-sphincteric fistulas as well as suprasphincteric and extrasphincteric fistulas (10).
Our current indications for the surgery are
low transsphincteric fistulas
high transsphincteric fistulas
potentially suprasphincteric/extrasphincteric fistulas where the tract traverses the intersphincteric space
recurrent fistulas
pre-existing continence issues
multiple tracks
In our opinion, contraindications to this approach are few, but may include
active perineal sepsis
active inflammatory bowel disease
malignancy
It is an evolving technique with literature that continues to mature; as such, these indications and contraindications will likely change. The experience thus far is that a LIFT can be used in almost any type of fistula as long as a portion of the tract traverses the intersphincteric space.
Certainly, there are fistulas that may be more difficult to treat with a higher failure rate including fistulas secondary to Crohn’s or radiation and rectovaginal fistulas. As more studies are done, these questions will hopefully be answered.
Preoperative Planning