Laparoscopic
Badma Bashankaev
Christina Seo
Indications/Contraindications
The indications for a laparoscopic low anterior resection with stapled coloanal or colorectal anastomosis (hereafter referred to as stapled low anterior resection [LAR]) are as follow:
Middle rectal tumors (5–10 cm from anal verge)
Lower rectal tumors (0–5 cm from anal verge), with a distal margin of ≥1 cm, with an extra 1 cm of rectum required to perform stapled anastomosis
This procedure is absolutely contraindicated only in patients with unstable hemodynamics such as acute myocardial infarction or severe sepsis such as fecal peritonitis.
The relative contraindications depend largely upon the experience of the surgical team. They include the following:
Morbid obesity
Advanced age
Severe cardiovascular or pulmonary disease
Liver cirrhosis
Large or enlarging abdominal aneurysm
Severe acute inflammatory bowel disease
Large abscess or phlegmon
Pregnancy
Presence of scars from multiple laparotomies
Coagulopathy or bleeding disorders
In cases where establishing pneumoperitoneum is contraindicated due to hemodynamic or pulmonary compromise, the laparolift (gasless laparoscopy) option may be considered.
Preoperative Planning
Informed consent is an obligatory part of every preoperative plan. A discussion with the patient regarding the risks, benefits, potential complications, and alternatives to the procedure provides a realistic gauge of the patient’s expectations. Specific to the laparoscopic
approach, the possibility of conversion to open surgery in cases of technical difficulties or intraoperative complications ought to be discussed. Intraoperative colonoscopy may be used for precise verification of the position of the lesion, the height of the rectal stump, and final evaluation of the anastomosis. If used routinely, this procedure should be added to the informed consent.
approach, the possibility of conversion to open surgery in cases of technical difficulties or intraoperative complications ought to be discussed. Intraoperative colonoscopy may be used for precise verification of the position of the lesion, the height of the rectal stump, and final evaluation of the anastomosis. If used routinely, this procedure should be added to the informed consent.
Preoperative evaluation of patients scheduled for stapled LAR consists of standard tests, rectal cancer staging, and any further assessments needed specifically for low rectal procedures. The steps needed to stage the rectal cancer and determine the appropriate surgical procedure(s) include:
Digital rectal examination
Assessment of size and degree of fixation of mid to low rectal tumors
Flexible sigmoidoscopy/rigid proctoscopy
Measurement of the level of lesion from the anal verge or dentate line
Biopsy of the lesion
Biopsy for pathologic examination
Diagnosis confirmation
Preliminary prognosis of disease
Colonoscopy
Exclusion of synchronous colonic lesions
Endorectal ultrasound with two-dimensional (2D) or three-dimensional (3D) sensors
Rectal wall penetration (T-stage)
Nodal involvement (N-stage)
Local lymph node involvement
Magnetic resonance imaging (MRI) of the abdomen and pelvis
Rectal wall penetration (T-stage) and evaluation of involvement of adjacent structures
Determination of resectability or need for en bloc resection
Lymph nodes involvement (N-stage)
Local and regional lymph node involvement
Computed tomography (CT) scan of the abdomen and chest
Detection of distant metastasis (M-stage)
Positron emission tomography (PET) scan
Verification of local and distant metastasis
Chest x-ray
Detection of distant metastasis
Evaluation of the patient’s overall physical fitness and determination of the patient’s operative risk are done with the following:
Internal medicine evaluation
Cardiology, renal, hepatology, pulmonology consults if required
Anesthesiology consult
Ideally before day of surgery
Complete blood count (CBC), complete metabolic panel (CMP) blood tests
Carcinoembryonic antigen (CEA) level for postoperative surveillance
ECG
Considerations specific to stapled LAR:
Preoperative counseling for stoma care with ileostomy/colostomy marking
Obtain the optimal position of the stoma
Permanent tattoo with India ink or henna of stoma site if seen ≥1 week before surgery
Skin marker with transparent medical dressing (Tegaderm™, 3M, St. Paul, MN) if seen less than a week before surgery
Provide initial education about ostomy maintenance
Preoperative surgical nurse visit
Explanation of surgical procedure, including bowel preparation, and postoperative fast track protocol
Scheduling of patient’s admission to the hospital
First step in establishing patient awareness of fast-track care protocol
Anal manometry in patients older than 65 years
Diagnosis of latent fecal incontinence and impaired sphincter mechanism
Current recommendations suggest offering patients with stage II (node-negative disease with transmural invasion) and stage III rectal cancer (node-positive disease) neoadjuvant chemoradiotherapy (nCRT). It is widely accepted that nCRT results in downstaging and downsizing of the tumor with a better likelihood for successful sphincter preservation by providing a safe distal margin of 2 cm. In the USA, nCRT therapy lasts for 5–6 weeks and consists of median radiation dose of 50.4 Gy (45–65 Gy), with 45 Gy to the pelvis and 5.4 Gy boost to the tumor over 28 fractions with fluorouracil (5-FU)-based infusions. The optimal interval after completion of nCRT to surgery is around 6 weeks; this is related to the progression of acute postchemoradiation inflammation to fibrosis while maintaining a safe period to allow tumor regression.
Patients are asked to stop taking medication containing aspirin and aspirin-like products 10 days prior to the surgery. The day before surgery, patient undergoes mechanical bowel preparation. Nil per os (NPO) status after midnight the night prior to surgery is requested to decrease the potential risk of pulmonary aspiration with resultant chemical pneumonia. The patient is admitted on the morning of surgery. Cross-typing of blood can be done either during preoperative evaluation or on the day of surgery.
Both perioperative antibiotic prophylaxis for the first 24 hours and DVT prophylaxis with subcutaneous injection of 5,000 units of heparin and/or pneumatic sequential pressure devices for the lower extremities are standard precautions.
Surgery
The operating room (OR) team consists of the operating surgeon, first assistant, camera assistant, scrub technician/nurse, and a circulating nurse. It is crucial that the OR team has a common understanding of the procedure and a firm knowledge of laparoscopic instruments and their handling. The surgeon and first assistant may share the camera driving throughout the case. In addition to having a solid familiarity with the surgical procedure, reverse camera driving and advanced laparoscopic skills are very important skills.
Typically, the surgeon and camera driver stand on the right side of the patient (opposite to the site of dissection), with the first assistant on the left side. During the operation, the position of surgeon may need to change in order to increase range of motion; for example, during the splenic flexure mobilization, the surgeon may need to stand between the legs of the patient.
At least two monitors are required for the laparoscopic LAR. One should be on the left side of the patient for the surgeon and camera driver, and another over the patient’s head or right shoulder for the first assistant.
A laparoscopic tray with a traumatic bowel or Babcock graspers is required. Two 30 degree 10-mm cameras and one 30 degree 5-mm camera should be placed in a thermos with warm sterile water, or in a special camera warmer.
Positioning
After the patient is brought into the OR, he or she is carefully transferred to the OR table. The anesthesiologist then intubates the patient and inserts a naso-/orogastric tube. The patient is placed in modified lithotomy using Allen® (Allen Medical Systems, Acton, MA) stirrups with legs oriented so that the toes, knees, and shoulders are in line. The knees should be slightly flexed and the thighs flattened parallel to the bed so that the surgeon can maintain the greatest range of motion of his hands and laparoscopic instruments.
The use of a Bean Bag placed directly on the table with both arms tucked can prevent sliding of the patient while using steep Trendelenburg and reverse-Trendelenburg positions. The patient’s extremities should be well padded to avoid any trauma at bony prominences.
It is important to provide 3–4 cm of exposure of the perineal area off the edge of the operating table before commencing the surgery to allow easy passage of the circular stapler. Additional care should be taken to regulate the temperature of the patient with the use of heating devices such as Bair Hugger®, Arizant Inc., Eden Prairie, MN.
If patient had a stoma site marked preoperatively, the site is marked with a needle tip to prevent losing the mark during the preparatory wash.
We routinely use ureteral stents for deep pelvic surgery. A urologist places these stents to facilitate safe laparoscopic pelvic dissection by providing tactile and visual confirmation of the safety of the ureter.
Rectal irrigation is undertaken with Betadine® Solution (aqueous solution of 10% povidone-iodine) (Purdue Products L.P., Stamford, CT). The abdomen is prepped and draped in the usual sterile manner, taking care to position the sterile towels along the anterior axillary line for proper trocar placement and across the xiphoid and pubis for possible laparotomy.
It is preferable to use laparoscopic draping with built-in pockets to attach the insufflation tubing, camera cord, light cable, and cautery cord around the perimeter of the patient’s abdomen. The Steri-Drape™ (3M™ Medical, St. Paul, MN) plastic pouches or other holsters are useful for organizing and securing the laparoscopic instruments onto the sterile field.
Technique
The laparoscopic-stapled LAR consists of several steps (Fig. 14.1). This procedure can be performed totally laparoscopically (port site wounds only) and laparoscopic-assisted (port sites and specimen extraction site). Both approaches start by establishing pneumoperitoneum. There are two common techniques of laparoscopic entry into abdominal cavity to maintain pneumoperitoneum—closed (Veress) and open (Hasson), based on surgeon preference.
The open Hasson technique is preferable due to its ease and minimal risk of injury to peritoneal structures. The incision is made above or below the umbilicus depending upon the height of the patient and the distance of the umbilicus from the pubis. An extension of this incision may be used for specimen extraction, thereby providing somewhat better cosmesis. The Hasson technique starts with a vertical 1.5-cm long skin incision with #15 blade scalpel or diathermy, dissecting the subcutaneous tissues to the level of fascia. The fascia is grasped with Kocher clamps or similar instrument to better visualize and incise that layer. Anchoring sutures are placed on the edges of the fascial incision with 2-0 Vicryl™ (Ethicon Inc., Summerville, NJ) or silk to form handles for the Hasson trocar. The preperitoneal fat is gently spread to expose the peritoneum, which is grasped with smaller clamps and divided, taking care to ensure that there is no intervening bowel. The 12-mm Hasson trocar is then introduced into the abdominal cavity and secured with the previously placed anchor sutures. The insufflation tube is attached and carbon dioxide pneumoperitoneum with a pressure of up to 15 mm Hg is established.
A 30-degree 10-mm camera is obtained from out of the warmer or thermos and attached to the light and video processor cables. White balance of the camera is done on a laparotomy gauze or any other uniformly white surface.