Eosinophilic Esophagitis

Eosinophilic esophagitis (EoE) is a disease that was virtually unheard of 20 years ago. Yet, in recent years, there has been an explosive increase in the number of children and adults afflicted with the disease along with our understanding of the fundamental pathogenesis and clinical management of this fascinating disorder. The pace of change continues to be rapid as can be attested to by the publication of three sets of EoE clinical guidelines since 2007. Furthermore, recent studies suggest that delay in diagnosis leads to an increase in dysphagia symptoms and the findings of fibrostenotic disease at the time of endoscopy. This observation has important implications for disease recognition and management.

Given our rapidly evolving understanding of EoE, now is a good time to get a good “lay of the land” of this disease. Ikuo Hirano, an international leader and pioneer in EoE, has assembled well-recognized experts in the field to provide you with a state-of-the-art, practical understanding of EoE for both children and adults in 2014. Topics you will find in this issue of Gastroenterology Clinics of North America include the epidemiology, clinical presentation, diagnosis, and management of EoE as well as a glimpse into what the future holds. In addition, articles dedicated to mechanisms of disease pathogenesis and complications complete this comprehensive assessment of the field at present.

I know that this issue of the Gastroenterology Clinics of North America will enhance your understanding of EoE and I hope you enjoy it.

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