Complications in Pediatric Robotic Urologic Surgery


Robotic procedure

Presentation (time)

Signs and symptoms

Evaluation

Treatment

Follow-up

Ureteral reimplantation

Urinary retention

Immediate

Lower abdominal pain, inability to void

Abdominal examination, possible bladder scan

Straight catheterization or indwelling catheter

If indwelling catheter, remove in 2 to 14 days

Ureteral obstruction

Immediate to 7 days

Decreased urine output, worsening hydronephrosis

Ultrasound

Retrograde ureteral stent or if unable, antegrade

Stent removal in 1 month, follow-up ultrasound afterward

Ureteral injury/urine leak

4–7 days

Lower abdominal pain, nausea, emesis, fever

Ultrasound, possible CT urogram

Retrograde pyelography with ureteral stent, indwelling catheter

Indwelling catheter removal in 5 days, stent removal in 1 month, follow-up ultrasound after

Pyeloplasty

Anastomotic leak

4–7 days

Abdominal pain, nausea, emesis, fever

Ultrasound

If stent is present, indwelling catheter and anticholinergics, if not, retrograde pyelography with ureteral stent versus nephrostomy

Indwelling catheter removal in 1 week, stent removal in 1 month, if nephrostomy, antegrade nephrostogram prior to removal, follow-up ultrasound after

Stent migration

Variable

Abdominal pain, nausea, emesis, urinary symptoms

KUB

Cystoscopy with possible ureteroscopy and stent placement

Stent removal in 1 month, follow-up ultrasound after

Complex reconstruction (appendicovesicostomy and/or augmentation cystoplasty, bladder neck reconstruction)

Stomal incontinence

Variable

Leaking at stoma site

Urodynamics, possible video urodynamics

Depending on severity and etiology, anticholinergics, endoscopic bulking agent injection, or surgical revision of channel

Clinical follow-up after procedure

Stomal stenosis

Variable

Difficulty catheterizing

Endoscopic evaluation of channel

Dilation versus surgical revision

Clinical follow-up after procedure

False passage

Variable

Difficulty catheterizing, hematuria with catheterization

Endoscopic evaluation of channel

Conservative management with indwelling catheter versus surgical revision of channel

If indwelling catheter remove in 1–4 weeks, if surgical revision remove catheter in 1 month, clinical follow-up after procedure

Small-bowel obstruction

Variable

Abdominal distention, nausea, vomiting

Acute abdominal series, possible CT scan with oral and IV contrast

Conservative management with NGT and parental nutrition versus surgical exploration

Clinical follow-up

Bladder stones

12 months or more

Hematuria, malodorous urine

Bladder ultrasound, possible KUB

Endoscopic versus percutaneous lithotripsy, open cystolithotomy

Ensure adequate drainage with possible need to irrigate bladder, clinical follow-up

Nephrectomy or heminephrectomy

Urine leak

4–7 days

Abdominal pain, nausea, emesis, fevers

Ultrasound

Retrograde pyelography with ureteral stent, possible indwelling catheter and anticholinergics

If indwelling catheter, removal in 1 week, stent removal in 1 month, ultrasound





Prevention (Preoperative)



Patient Positioning


The first step to preventing complications in pediatric robotic surgery is proper patient positioning with adequate padding. Although positioning varies between surgeons and procedures, several universal measures for the prevention of nerve injury are noted below. In the supine position, maintaining upper extremity abduction to less than 90° reduces the risk of brachial plexus injury. Furthermore, ensuring a supinated or neutral position of the forearm prevents ulnar nerve compression [4]. The use of Trendelenburg position should be avoided for prolonged periods as this can place the pediatric patient at risk for both positional migration and cardiopulmonary changes. After a patient is secured to the operating room table, communication with the anesthesiologist is vital to ensure that respiratory excursion is not compromised. Rehearsal positioning of the bed prior to docking of the robot can confirm proper secure positioning since the patient position should not migrate once the robotic is docked. With lithotomy positioning, care must be taken to limit pressure of the fibular head on the peroneal nerve. And during flank positioning, an axillary roll placed between the chest walls caudal to the dependent axilla and the bed prevents compression of the brachial plexus.

Although limited data exists regarding peripheral nerve injury during robotic procedures in the pediatric population, the adult experience has shown that upper extremity ulnar and brachial plexus injuries are the most common [4]. Review of a multicenter database of 880 pediatric robotic urologic surgeries identified one patient with knee numbness and another with facial swelling that resulted from positioning [5]. These complications were self-limited and resolved spontaneously similar to the majority of positioning-related injuries. However, if prolonged sensory or motor deficits are persistent, referral to pediatric neurologic specialists for further evaluation may be indicated.


Intraoperative



Intra-abdominal Access


There are two classic techniques for intra-abdominal access: Veress (closed) and Hasson (open). The closed technique consists of a Veress needle (blunt-tipped, spring-loaded, inner stylet surrounded by a sharp needle) that is inserted into the abdominal cavity without visualization. The blunt tip extends forward to protect the abdominal viscera and vasculature from the sharp needle after lower resistance is encountered upon entry into the peritoneal cavity. The needle is often passed at a 45 ° angle in nonobese patients and adjusted to 90 ° in obese patients to avoid visceral and vascular injuries. Once the needle is placed, aspiration and/or injection of fluid prior to insufflation is recommended to confirm proper placement [6, 7].

The open Hasson technique can be used in all patients and is especially preferable for patients with obesity, prior abdominal surgery (with possible intra-abdominal adhesions), or failed Veress needle access. After the initial skin incision, a pair of stay sutures at the fascia level can assist with the fascial opening and allow for peritoneal entry under direct vision and therefore without the need for confirmation of intraperitoneal placement as with the closed technique [6]. Once the trocar is placed, the stay sutures can be used to secure the port in place.

Regarding the prevention of access complications, the open technique is often utilized since the anteroposterior diameter of the pediatric abdomen is relatively narrow. Other recommendations include decompression of the stomach with a nasogastric tube and of the bladder with Foley drainage to avoid injury to a distended intra-abdominal organ . Subsequent port placement should always be performed under direct visualization and with blunt-tipped trocars and especially for accessory ports that may be placed outside of the visual field (behind the camera). In patients with previous abdominal surgeries, ventriculoperitoneal shunts, and/or previous bladder reconstruction surgery, access superior to the umbilicus may facilitate safe entry.

Intra-abdominal access injuries are often recognized immediately and can involve vasculature, intestine, or nerves, with an incidence as high as 5.4% with the Veress technique [7]. Passerotti et al. and others noted that the best predictor for avoiding complications was the surgeon’s previous experience with laparoscopic procedures [810]. The treatment of access complications will be addressed below.


Vessel Injury


Vessel injury is the most common type of intraoperative complication with minimally invasive surgery . A large multi-institutional analysis showed a complication rate for vascular injury of 0.4% in 880 pediatric robotic urologic procedures [5]. Vascular injuries can occur during intra-abdominal access, port placement, instrument insertion, cauterization of surrounding structures, excessive traction, and careless handling of needles. Common preventive measures include the introduction of ports and instruments with care under direct visualization, dissection with caution to surrounding tissues and vessels, and the avoidance of excessive traction. A set of vascular open instruments should always be available in case rapid conversion to an open procedure is needed. Any vessel injury should be identified and addressed immediately to avoid major blood loss and deterioration of hemodynamic status. If the bleeding source is venous, direct pressure or cauterization can often help to control this bleeding [9, 10]. If a major vessel is injured, the trocar should be left in place and rapid conversion to open exploration is warranted. For minor vessels, if the bleeding cannot be controlled laparoscopically, conversion to open surgery is also recommended [5, 11, 12]. If vascular entry of CO2 during insufflation is suspected, the patient should be placed in the left lateral decubitus position to trap the embolus in the right atrium. Treatment of this potentially catastrophic complication can often be accomplished with central line aspiration and transesophageal ultrasonography [6].


Bowel Injury


Intestinal injury can occur during intra-abdominal access, port placement, and instrument insertion, as well as with electrocautery. The extent of these injuries can vary from simple serosal tears to full-thickness enterotomies. Often, the careful handling of instruments and needles in the abdominal cavity can help to prevent these injuries. In addition, the appropriate placement of insulation tip covers can prevent unintentional cauterization of adjacent tissues. However, for patients with a history of previous abdominal surgeries and/or ventriculoperitoneal shunt placements, a higher risk of bowel injury may be present due to the presence of intra-abdominal adhesions.

For serosal tears, the repair should include imbricating seromuscular sutures. If a full-thickness enterotomy is seen, repair with one or two layers of braided absorbable suture is needed. If multiple tears are present in a bowel segment, bowel resection and primary anastomosis, or intestinal diversion, may be required. If a bowel injury is not immediately identified at the time of surgery, patients can present a few days later with signs and symptoms of peritonitis (i.e., abdominal pain, ileus, leukocytosis, fever with tachycardia, and hypotension) that can progress to sepsis and shock in some cases. Early identification of these injuries in the postoperative period is critical and usually leads to immediate surgical intervention. Laparotomy with intestinal repair or diversion as well as evacuation of debris, secretions, and pus is necessary along with copious irrigation of the peritoneal cavity with antibiotics and saline. An intra-abdominal drain is left in place to prevent re-accumulation of a closed fluid collection [5, 6, 12]. Consultation with the general surgery service is usually recommended for these cases.


Needles


Lost needles during a robotic procedure should be avoided at all costs as they can lead to potential injury as well as additional operative time during the search for the lost needle. Maintaining strict and accurate needle counts during surgery is essential to prevent misplacement of a needle. In addition, the use of a single needle at a time and the verbal reporting by the bedside assistant of the introduction and removal of needles are critical for maintaining accurate counts. If a needle is lost during surgery, it is recommended to avoid movement of the instruments or intestines since movement can alter the original position of the needle and lead to increased difficulty of the search. Undocking of the camera as well as an intraoperative X-ray can assist with locating the needle if initial visual inspection is not successful. Once a lost needle is found, assessment of the bowel and surrounding structures should be performed to evaluate for injury and assess whether repair is warranted [12].


Postoperative Complications



Ureteral Reimplantation



Urinary Retention


Urinary retention rates have been reported as low as 0.5–1.5% after robotic extravesical ureteral reimplantation, which is lower than the historical rate associated with open surgery [1315]. Patients with bilateral high-grade reflux and severe preoperative dysfunctional elimination syndrome (DES) are known to be at higher risk of developing urinary retention after surgery [1517]. Once the postoperative urethral catheter is removed, it is important to ensure that patients are voiding on their own prior to discharge. If a patient is unable to void, clean intermittent catheterizations or an indwelling catheter can be used. Conservative management is recommended, as resolution of urinary retention usually occurs in 2–14 days, after which a voiding trial usually results in spontaneous voiding [14, 16, 1821].


Ureteral Obstruction


Detrusorraphy (closure of the muscle flaps) during robotic reimplantation can be accomplished via several techniques, top-down or bottom-up, and with the use of interrupted sutures or running sutures [22]. In addition, some authors recommend a ureteral advancement stitch and/or an alignment stitch at the apex to prevent excessive angulation of the ureter during reimplantation and potential obstruction, although the advancement stitch may increase the risk of obstruction as well [16, 17]. Previous studies have reported an incidence of ureteral obstruction in patients undergoing RALUR as high as 4–5%, but this may be a technical issue as this appears to be limited to a few centers [14, 16, 1822]. Ureteral obstruction may result from aggressive handling of the ureter during surgery, cautery injury during the dissection, and severe postoperative bladder edema. These patients often present during the first postoperative week with abdominal distension and pain, decreased urine output, increased hydronephrosis, and elevated post-void residual volumes. If a ureteral obstruction has occurred, placement of a ureteral stent and possible future surgical repair to repair the obstructed segment may be needed. Serial ultrasonography is useful to monitor the status of the hydronephrosis and hydroureter.

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Jan 26, 2018 | Posted by in UROLOGY | Comments Off on Complications in Pediatric Robotic Urologic Surgery

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