Chapter 15 ACUTE DIARRHOEA
• Acute infectious diarrhoea is common worldwide and is responsible for significant patient hospitalisation and mortality.
• Acute diarrhoea is defined as an increase of stool frequency (greater than three stools per day or at least 200 g of stool per day) lasting less than 14 days.
• Assessment should focus on the severity of illness, need for rehydration and the identification of the aetiology of the illness on the basis of history and clinical findings.
PATHOPHYSIOLOGY
The symptoms of acute diarrhoea vary according to the portion of the intestine that is involved in the disease process. Infectious diarrhoea is often associated with symptoms of nausea, vomiting and abdominal cramps.
AETIOLOGY
Infectious and non-infectious causes may be responsible for acute diarrhoea (Table 15.1).
Bacteria | Viruses |
Protozoa |
Infectious causes include bacteria, viruses and protozoa.
Bacteria
• Campylobacter: most common bacterial cause usually from poultry, meat, dairy products and contaminated water.
• Escherichia coli: O157:H7: usually from contaminated meat, can be associated with haemolytic uraemic syndrome.
Viruses
Viruses cause the vast majority of all cases of acute diarrhoea.