A family history of liver disease

Chapter 42 A FAMILY HISTORY OF LIVER DISEASE






WILSON’S DISEASE









ALPHA1-ANTITRYPSIN DEFICIENCY (A1-ATD)




Alpha1-antitrypsin deficiency (α1-ATD) is a genetic disorder (autosomal/recessive) that predisposes to chronic liver disease and chronic obstructive pulmonary disease (COPD). It affects 1 in 2,000–5,000 individuals.


α1-ATD is a glycoprotein mainly produced by hepatocytes in the liver. Its main function is to protect tissues against proteases, such as neutrophil elastase.




Mar 29, 2017 | Posted by in GASTROENTEROLOGY | Comments Off on A family history of liver disease

Full access? Get Clinical Tree

Get Clinical Tree app for offline access