Ultrasound-Augmented Clinical Examination and Intraoperative Pelvic Floor Ultrasonography



Fig. 15.1
2D endovaginal view of the sacrospinous complex obtained with a BK triplane 8818 transducer (BK Ultrasound, Analogic, Peabody, MA, USA), the pudendal nerve which goes between the sacrospinous ligament and sacrotuberous ligament travels along the neurovascular bundle (blue). T transducer, AR anorectum, IC iliococcygeus, SSL sacrospinous ligament, STL sacrotuberous ligament, IS ischial spine. © Shobeiri



In our practice, we have seen many patients with pain originating after a mesh procedure develop pelvic floor myalgias, pelvic pain, and dyspareunia. A focally painful segment of hardened mesh due to shrinkage of the vaginal mesh implant may lead to primary vaginal pain syndromes and dyspareunia following vaginal mesh use [2]. A recent case series reported high incidence of pain along contracted mesh sites. Severe vaginal pain and focal tenderness are reported which can be reproduced by palpation of the mesh segment. The main clinical features include groin pain, suprapubic pain, dyspareunia, vaginal tightness, severe vaginal pain with movement, and vaginal shortening on vaginal examination. Over-tensioning of the mesh arms during implantation, and collagen deposition and contraction within the mesh pores are reported to be responsible for mesh hardening and nerve fiber entrapment [2]. This complication needs to be more robustly characterized and addressed in all studies reporting outcomes with synthetic transvaginal mesh-augmented prolapse repairs. However, it is difficult to characterize this complication, as the symptoms are often similar to other mesh-related complications or are compounded by chronic pain syndromes or myalgias. The pain syndromes related to mesh, like other pain syndromes, can be debilitating and have a profound adverse psychosocial effect in patients who suffer from it. Thus, treatment of pain related to mesh is typically multimodal and should be promptly recognized and instituted. Muscle relaxants and analgesics may improve pain in some individuals and are frequently first-line therapies. Physical therapy has been shown to improve some myalgias, as well as some neuropathies, and should be attempted prior to more aggressive intervention. In some situations, the mesh is clearly tight and tender, and the pain can be clinically reproduced by palpation of a tight band of mesh on vaginal examination. In these patients, surgical removal of the mesh may be preferred since the removal often has rates of improvement in pelvic pain and dyspareunia exceeding 70% [3]. Dyspareunia related to mesh exposure should typically be treated with surgical revision.

Although clinical examination and urodynamic study are the basic methods in the diagnostics of incontinent women, the significance of perineal pelvic floor ultrasound (pPFUS) is often mentioned in many more recent publications as the method enabling the assessment of the position of the urethra, its anatomical relations, mobility, and hyper-rotation. pPFUS is a widely available diagnostic method that may be performed by every clinician involved in pelvic floor diagnostics; it does not require special transducers and sophisticated scanners. The equipment used for pPFUS is widely accessible in obstetrics, radiology, gynecology, urology, surgery, and other specialties; thus, the access is easy and no extra investment is needed. Ultrasound has been used in the office or the operating room for drainage of hematomas and seromas. This anatomical access, however, does not allow for getting complete information about the complex anatomy of the urethra and its relations to the bladder, elements of the levator ani, and the vaginal walls, including pubocervical fascia. With this knowledge comes the ability to detect the cause of problems that have eluded us and to invent different ways of correcting the root cause of these problems. Two dimensional (2D) or three dimensional (3D) endovaginal ultrasound has become widely available. In a patient with vaginal tenderness and implanted vaginal mesh, one can use an endovaginal or an endoanal probe and map the vagina in a blinded fashion with a long Q-tip. With an endovaginal probe a long Q-tip is introduced along side the probe into the vagina. With an endoanal probe, the Q-tip is visualized vaginally (Fig. 15.2).

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Fig. 15.2
2D endoanal view of Q-tip mapping of vagina to locate painful area. A anterior, C cephalad, P posterior, Q Q-tips, anorectum, EAS external anal sphincter, LP levator plate. Yellow arrows outline the beginning and end of the mesh. The yellow arrow tip points to the tip of the Q-tips. © Shobeiri



Intraoperative Ultrasound-Guided Botox of the Pelvic Floor


Recent applications of botulinum toxin A (BoNt-A) have included treatment of refractory pelvic pain and pelvic floor spasm [4, 5]. Electrophysiological or ultrasound guidance can facilitate BoNt-A injection accuracy , but clinical landmarks and palpation are often used for superficial muscles. In a study evaluating the accuracy of manual needle placement in the gastrocnemius muscles (GC), guided only by anatomical landmarks and palpation, bilateral limbs from 30 cadavers were used to evaluate ink injection into the GC . One anatomist and one orthopedic surgeon verified the accuracy of manual needle placement post injection by calf muscle dissection. Injection was considered a failure if the ink was not located in the head of the target GC. One hundred twenty-one practitioners were evaluated. Fifty-two injections were successful (43%), and 69 failed (57%). This result was unrelated to injector experience (P = 0.097). The findings showed a poor success rate, regardless of injector experience. Therefore, muscle palpation and anatomical landmarks were insufficient to ensure the accuracy of BoNt-A injections, even for large, superficial muscles [6]. There has been reported variability in patient response with this levator ani muscle (LAM) BoNt-A injection, and response rates may vary due to anatomic variations of the pelvic musculature (Fig. 15.3). 3D endovaginal ultrasound guided-injection to the LAM is a novel application of injecting BoNt-A in patients with levator ani spasm (Fig. 15.4). Using the endovaginal probe, the needle is readily visualized in real time and injections can be performed in a directed fashion. The potential advantages of this method are many, and include direct visualization of adjacent anatomical structures, direct visualization of the targeted muscle, with the possibility of repositioning the needle in cases of misdistribution or distortion of anatomy, and avoidance of potential intravascular injections. The long-term efficacy of this approach is currently the subject of an ongoing study.

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Fig. 15.3
Blind finger guided injection of the levator ani muscle via a transperineal approach. We prefer this method as it has decreased bleeding as the needles do not traverse vascular vaginal epithelium. The needle is placed in location via US guidance and then botulinum toxin injection is carried out. © Shobeiri


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Fig. 15.4
3D volume from BK 8838 probe (BK Ultrasound, Analogic, Peabody, MA, USA) showing left (L) sagittal view of the needle in the puborectalis muscle in the same patient as in Fig. 15.3. V vagina, PB pubic bone, AR anorectum, PRM puborectalis muscle. The arrows show the path of the needle. © Shobeiri


Intraoperative Ultrasound-Guided Sling Release


A useful utilization of 3D endovaginal ultrasound is that of clear visualization of synthetic implants, such as midurethral sling materials. Surgical removal of these synthetic materials can be challenging in nature, especially when performed in patients remote from surgery. The sling can be anywhere except where it should be (Fig. 15.5). Surgeons may desperately open the vaginal epithelium to expose the urethra not knowing if the sling was part of the scar that was cut. We have seen many patients who were told their slings were released, only for us to find intact slings by ultrasound. Inability to be 100% sure that the sling has been cut has severe ramifications for the patient. Such patient may be subject to additional surgeries or neuromodulation, neither of which would work if the sling is not released. 3D endovaginal ultrasound provides real-time visualization of the midurethral sling material (Figs. 15.6 and 15.7). It allows for visualization of the precise location of the synthetic, relative to the urethrovesical junction, as an adjunct to surgical planning, or allows for real-time needle localization of the location of the material, just prior to surgical prepping [7]. Besides localizing intact slings, ultrasound can also be used for localization of sling and mesh remnants (Figs. 15.8, 15.9, and 15.10). Sometimes patients with distant history of procedures and persistent pain are found to have pieces of permanent sutures floating around or seemingly trying to work their way out of the body. The pain can be localized to these elements by the same long Q-tip testing under ultrasound guidance described above (Figs. 15.11 and 15.12).

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Fig. 15.5
3D axial view of a sling cephalad in the pelvis. On the right side (R) the sling is close to the uroepithelium of the bladder and on the left side (L) it is entering the levator ani muscle. B bladder, V vagina, AR anorectum. © Shobeiri


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Fig. 15.6
2D mid-sagittal view of the pelvis. During surgery, in cases where the sling is not palpable, a needle is inserted into the sling which facilitates location and division of the sling. B bladder, PS pubic symphysis, S sling, N needle, U urethra. (From Mukati and Shobeiri [7], with permission)


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Fig. 15.7
Once the sling is localized, the needle is followed through a small incision and the sling is cut. © Shobeiri


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Fig. 15.8
2D endovaginal right sagittal view of a right retropubic tape sling arm remnant. B bladder, C caudad, A anterior. © Shobeiri


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Fig. 15.9
3D endovaginal axial a left transobturator tape remnant. U urethra, PS pubic symphysis, V vagina, AR anorectum, L left, R right. Arrow heads point to the ends of the tape. © Shobeiri


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Fig. 15.10
3D endovaginal coronal view of a right transobturator tape remnant. C cephalad, P posterior. The arrows point to the ends of the tape. © Shobeiri

Jul 11, 2017 | Posted by in UROLOGY | Comments Off on Ultrasound-Augmented Clinical Examination and Intraoperative Pelvic Floor Ultrasonography

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