The Biologics Explosion Era


Product

Source

Cross-linked

Sterilization method

Alloderm (Lifecell, Branchburg, NJ)

Human dermis

No

Ionic

Allomax (Davol, Warwick, RI)

Human dermis

No

E beam

Flex HD (Ethicon, Sommerville, NJ)

Human dermis

No

Ethanol

Strattice (Lifecell, Branchburg, NJ)

Porcine dermis

No

Gamma irradiation

Permacol (Covidien, Norwalk, CT)

Porcine dermis

Yes

Ethanol

Collamend (Davol, Warwick, RI)

Porcine dermis

Yes

Ethanol

Xenmatrix (Davol, Warwick, RI)

Porcine dermis

No

Gamma irradiation

Surgimend (TEI Biosciences, Boston, MA)

Bovine fetal dermis

No

Ethanol

Veritas (Synovis, St. Paul, MN)

Bovine pericardium

No
 
Periguard (Synovis, St. Paul, MN)

Bovine pericardium

Yes
 
Surgisis (Cook, Bloomfield, IN)

Porcine intestine

No

Ethanol




Quilting


The use of biologic mesh has been used more frequently, especially with the predominant use of acellular dermal matrix (ACM). Historically, individual pieces were small and therefore had to be quilted together. Initially, it was felt that the acellular dermal matrix quilts could be sutured to the fascial edge with acceptable outcomes (Figs. 5.1 and 5.2ad). This concept was inconsistent with general principles learned with synthetic mesh experiences [13, 6].



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Fig. 5.1
One of the very first reported cases in which the acellular matrix was used in 2001. It illustrates the quilting of the small pieces of ACM to each other and to the fascial edge

Jun 13, 2017 | Posted by in ABDOMINAL MEDICINE | Comments Off on The Biologics Explosion Era

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