Left and Sigmoid Colectomy for Malignant Disease


Fig. 17.1

Left colectomy anatomy


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Fig. 17.2

Laparoscopic left colectomy ports



The first step after establishing pneumoperitoneum and port placement is to explore the abdomen to rule out any metastatic disease and identify the lesion in the colon. The patient is positioned in steep Trendelenburg with right tilt so that the left side is up, and the small bowel is swept to the right to expose the left colon mesocolon. The superior rectal artery is then identified at the level of the sacral promontory. This is facilitated by retracting and tenting the superior rectal artery to the anterior abdominal wall to trace to its origin and opening the peritoneum from below the sacral promontory to the inferior mesenteric artery (IMA) origin on the aorta. The retroperitoneum is swept posteriorly until the left ureter is identified and protected as shown in Fig. 17.3. The IMA is isolated and ligated (can use clips, energy device, stapler, and vessel loop) as shown in Fig. 17.4. The inferior mesenteric vein (IMV) is then identified by separating the mesentery from the retroperitoneum to the inferior border of the pancreas. The IMV is then isolated and ligated (can use clips, energy device, stapler, and vessel loop) as shown in Fig. 17.5. The sigmoid colon and descending colon are retracted medially to free all the lateral attachments along the white line of Toldt, and the omentum is reflected cephalad to the transverse colon to expose the transverse colon and splenic flexure. In order to mobilize the splenic flexure, the superficial peritoneal plane between the omentum and transverse colon is opened toward the midline to enter the lesser sac, and the splenic flexure is then retracted medially and caudally to divide the peritoneal attachments to the inferior border of the pancreas. The splenocolic ligament is divided. By detaching the mesocolon off the kidney at Gerota’s fascia, the last attachments of the colon can be taken down sharply to achieve complete mobilization of the splenic flexure.

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Fig. 17.3

Identifying the left ureter


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Fig. 17.4

High ligation of the inferior mesenteric artery


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Fig. 17.5

High ligation of the inferior mesenteric vein


The identification of the proximal and distal points of transection can be performed with the assistance of indocyanine green enhanced fluorescence as shown in Fig. 17.6. An intracorporeal transection of the rectosigmoid junction is performed with the laparoscopic stapler at the confluence of the taenia coli. The specimen can be extracted through an extended off midline lower-quadrant trocar site (such as the 12 mm trocar site) or a suprapubic (Pfannenstiel) incision, a technique that is associated with a lower hernia rate.

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Fig. 17.6

Perfusion assessment


The descending colon can be transected at least 5 cm proximal to the tumor, and the anvil of a circular stapler can then be secured in the colon with a purse-string suture. The perineal operator then inserts the circular stapler transanally and deploys the pin through the midportion of the staple line of the rectal stump to complete an end-to-end colorectal anastomosis. An alternative approach would be to perform a side-to-end colorectal anastomosis by placing the anvil through the anti-mesocolic border of the descending colon. In either case, the anastomotic rings are checked for intactness and sent to pathology as additional proximal and distal margin. An air leak test of the anastomosis is performed with endoscopic assessment under laparoscopic visualization. Before closing, reassess if any unexpected findings during the surgery would warrant an unplanned diverting ostomy or placement of a drain. Several randomized trials and a meta-analysis suggest that routine use of drains for left colectomy is not recommended [19].


Pitfalls, Troubleshooting, and Special Considerations


Difficulty Identifying the Ureter


The left ureter should be clearly identified and safely dissected free of the left colon mesentery prior to the division or the IMA or the IMV. A ureteral stent may be inserted at the discretion of the surgeon. To help facilitate identification, these maneuvers may be taken in a step-wise fashion: access the retroperitoneum at the level of the superior rectal artery at the sacral promontory, identify the IMV, and open the medial aspect of the peritoneum to develop a plane in the retroperitoneum. Dissection can proceed caudally until the sacral promontory to identify the ureter. As an alternative to locate the ureter, mobilize the colon in a lateral to medial fashion to completely expose it, utilize a hand port, or convert to open to directly palpate for the ureter.


Difficulty with Reach


Resection of a proximal left colon lesion (splenic flexure, proximal descending) may require division of both branches of the middle colic artery to allow the proximal transverse colon to reach the rectal stump for anastomosis. The division of the left colic artery, marginal, and the middle colic vessels can lead to poor perfusion of the remaining transverse colon and can lead either to evident intraoperative colonic ischemia or to an under-perfused colorectal anastomosis with associated complications such as anastomotic leak, stricture, and segmental narrowing of the transverse colon. In cases where the transverse colon does not have adequate blood supply or cannot reach the rectum, if maintenance of the right colon is preferred, a retroileal right colon to rectum anastomosis may be performed versus an extended right colectomy with an ileosigmoid or ileorectal anastomosis.


Locally Advanced Tumors


As mentioned earlier in this chapter, T4a tumors can be approached laparoscopically with caution and can be completely removed. When there is clear invasion of an adjacent organ by a T4b tumor, conversion to an open approach is recommended [8]. En bloc resection of the colon and involved organ should be performed with the goal of achieving R0 resection.


When to Consider Conversion


The surgeon should consider conversion to a different approach if there is failure to progress over a significant period of time. Furthermore, excessive bleeding, unexpected organ injury, significant amount of adhesions, and difficulty in obtaining a high ligation of the vessels should prompt the surgeon to consider changing the surgical approach either to open or to another laparoscopic technique that can assist with solving the occurring problem. Strategies that can enhance the surgeon’s ability to deal with intraoperative difficulties or complications would include the placement of additional ports or hand assistance. If these strategies fail, the case should be converted to open surgery.


Outcomes


Laparoscopic colectomy for colon cancer has been found to have short-term benefits relative to open surgery and to be as safe and efficacious as open surgery. The COST trial published in 2004 was the initial large multicenter study group with almost 900 patients randomized to either open or laparoscopic approaches, with no differences found in overall survival or disease-free survival [3, 4]. This was followed by the UK CLASICC trial in 2005 and the European COLOR trial in 2009 which echoed similar findings [57]. More recently, the Australian Laparoscopic Colon Cancer Study trial conducted across Australia and New Zealand in 2012 and the Japanese JCOG0404 trials have continued to demonstrate and uphold the short-term benefits for the laparoscopic approach without differences in long-term overall survival, disease-free survival, and recurrence rates [20, 21]. The results of these five trials are summarized in Table 17.1.
May 2, 2020 | Posted by in GASTOINESTINAL SURGERY | Comments Off on Left and Sigmoid Colectomy for Malignant Disease

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