Laparoscopic Lateral-to-Medial Right Colectomy
Joshua H. Wolf
Ido Mizrahi
INDICATIONS/CONTRAINDICATIONS
The indications for performing a laparoscopic right colectomy can be divided into three groups:
Neoplasia
Endoscopically unresectable colonic polyps: Despite recent endoscopic innovations such as endoscopic mucosal resection (EMR) and endoscopic submucosal dissection (ESD), some colonic lesions are still found to be unresectable and necessitate colectomy.
Colonic/appendiceal cancer: Tumors in the appendix, cecum, ascending colon, or hepatic flexure are the most common indications for performing a right colectomy. Tumors in the transverse colon more commonly require an extended right colectomy.
Carcinoid: When this neuroendocrine tumor is found in the appendix, terminal ileum, or cecum, a right colectomy is needed.
Inflammation
Crohn’s disease: Patients with Crohn’s disease may present with inflammatory, fistulizing, or stricturing disease. These operations are typically more technically demanding than surgery for cancer. Intraoperative findings such as a large inflammatory mass, interloop abscesses, and fistulas to the sigmoid colon may pose technical difficulty and ultimately lead to conversion to open surgery. Strictures may be missed because of limited tactile sensation and the surgeon should consider extracorporeal palpation.
Right colonic diverticulitis (RCD): Although RCD has been reported to be a rare disease in Western countries, it is very common in East Asia and specifically in Korea, with an incidence of 1 case per every 2.9-17 cases of appendicitis. RCD is especially common among males in their relatively early years.
Other Indications
Ischemia: When ischemia is preoperatively suspected, the entire small and large bowel should be carefully inspected. Such cases are typically addressed with a laparotomy.
Pneumatosis intestinalis: When correlating with other clinical signs of nonviable bowel, pneumatosis intestinalis requires immediate surgery with resection of the affected section of the colon.
Iatrogenic perforation: The incidence of colon perforation during diagnostic and therapeutic colonoscopy ranges between 0.07% and 0.1%. The risk increases to 0.2% after EMR and is as high as 5% after ESD. It is reasonable to schedule an ESD in the operating room followed by surgery if the ESD has failed.
Cecal volvulus: This is a rare cause of intestinal obstruction caused by excessive mobility of the cecum.
Hemorrhage: Segmental colectomy for lower gastrointestinal hemorrhage is unusual because the bleeding source is difficult to localize. However, a right colectomy can be warranted if an arteriovenous malformation or other bleeding pathology is definitively localized to the right colon.
Incidental finding during laparoscopy for other etiologies: mass, ischemia.
There are no clear absolute contraindications for use of laparoscopy in performing right colectomy. Relative contraindications include the following:
Large mass requiring an incision for extraction
Adhesions from prior abdominal surgery
Limited surgeon’s experience
PREOPERATIVE PLANNING
Proper preoperative patient evaluation focusing on relevant history is crucial to help realize satisfactory surgical outcomes. Close attention should be given to factors that may alter surgical planning.
History and Physical Examination
Comorbidities: Attention should be given to connective tissue diseases and rheumatologic disorders requiring steroid treatment as these may impair anastomotic healing.
Medications
Steroids: The type, dosage, duration, and time of last dose should be clearly documented. Some patients may need a perioperative stress dose and a diverting loop ileostomy depending on tissue fragility.
Biologics: As for steroids, the type, dosage, duration, and time of last dose should be clearly documented. It is controversial whether a period of waiting before operating is necessary. It has been suggested to wait approximately 4-6 weeks between the last dose of biologic therapy and surgery.
Chemotherapy: Although neoadjuvant chemotherapy is not standard of care for colon cancer, some patients with metastatic disease may require neoadjuvant chemotherapy and surgery should be delayed approximately 4 weeks after the completion of treatment.
Previous surgery: All previous operative reports should be closely reviewed, with specific attention to the remaining length of bowel, type of anastomosis, and postoperative complications.
Family history: Family history should be reviewed for colitis, colorectal cancer, and any other relevant cancers that may suggest genetic predisposition to colon cancer.
Pathology: It is highly advisable to review the pathology slides at your own institution with a dedicated gastrointestinal pathologist if possible, specifically for patients with inflammatory bowel disease (IBD) or following resection of a malignant polyp.
Colonoscopy: Colonoscopy reports should be reviewed preoperatively and available at the time of the surgery. Findings should be discussed with the performing endoscopist. Tattooing should be done with India ink in multiple quadrants distal to the tumor to assure that the tattoo is visible on the serosal surface and not hidden by the mesentery. Make sure other areas have not been previously inked to minimize confusion at the time of surgery. When suspecting IBD, it is advised to take multiple biopsies of normal-appearing colon.
Physical examination: During the physical examination, the surgeon should be especially attentive to prior incisions, previous stoma sites, hernias, masses, lymph nodes, and body habitus with a calculated body mass index.
Labs/Imaging
Routine testing: Complete blood count and a comprehensive metabolic panel are routinely ordered. Coagulation studies should be ordered if indicated.
Cancer related: Baseline carcinoembryonic antigen (CEA) should be taken before surgery.
Nutritional status: Albumin and pre-albumin should be tested to assess the patient’s nutritional status. Preoperative enteral or parenteral nutritional support should be considered in clinically malnourished patients.
Imaging: Computed tomography (CT) of the chest, abdomen, and pelvis with oral and intravenous contrast are mandatory for cancer patients. Prior imaging should be reviewed with a specialized abdominal radiologist with specific attention to the location of the lesion, involvement of lymph nodes, vascular and urinary abnormalities, and metastasis to other organs. Patients with IBD are better evaluated with CT or magnetic resonance enterography.
Selecting a Surgery: Lateral Approach or Medial Approach?
There is essentially no difference in surgical outcomes between the two approaches, as is reviewed in a later section of this chapter. Hence, the surgeon should choose the most familiar and comfortable approach based on prior training and experience. There are, however, some inherent advantages and disadvantages of each method. The advantages of the lateral approach (LA) are (1) early identification of key structures such as the right ureter and duodenum and (2) use of the same dissection as in the open technique. The advantages of the medial approach (MA) are (1) early ligation of the vascular ileocolic pedicle, theoretically preventing liberation of tumor cells into mesenteric circulation and (2) the preservation of the lateral colonic ligament until the end of the mobilization, which helps with right colon retraction and exposure. MA may not be feasible under conditions in which the right colon mesentery is fixed to the retroperitoneum, for example, in cases with significant malignant adenopathy involving the ileocolic pedicle or extremely thickened mesentery due to Crohn’s disease or morbid obesity.
Mechanical Bowel Preparation with Oral Antibiotics
The role of mechanical bowel preparation (MBP) with oral antibiotics remains controversial. Some authors have shown no advantage, whereas others have shown that MBP with oral antibiotics reduces the rates of anastomotic leak, surgical site infection, and postoperative ileus. The authors advocate for routine use of MBP with oral antibiotics not only for the reasons mentioned but also for other technical reasons. The ability to “palpate” the bowel with laparoscopic instruments is limited without preparation. Furthermore, it is practically impossible to perform an intraoperative colonoscopy, if need be, without preparation. Lastly, if proximal diversion is unexpectedly required, MBP ensures that the remnant colon will be evacuated and clean rather than full of stool.
PREOPERATIVE COUNSELING
It is important to set realistic expectations with the patient regarding the length of the operation (approximately 2-3 hours), length of hospital stay (typically 2-3 days), recovery time (very individual, but approximately 1-2 weeks), and future bowel function, which should not be significantly altered in right colectomy. The authors counsel all patients regarding the possibility of a diverting ostomy, and practice bilateral stoma marking for all patients scheduled for an elective colectomy. Some may prefer to mark only patients at high risk for diversion, reducing workload from enterostomal therapists and anxiety from patients.
For certain patients, prophylactic cystoscopy and ureteric stents should be discussed as well. Although indications are not clearly defined, stents are generally used for reoperative cases, large tumors, previous radiation therapy (less relevant for a right colectomy), diverticulitis, fistulas, Crohn’s disease, and obesity.
SURGERY
Positioning
Secure patient positioning is essential for a successful laparoscopic right colectomy, which requires rotation of the surgical bed to several extreme angles. Foam padding must be carefully placed to avoid pressure injury, especially in obese patients. Appropriate time and focus should be dedicated to this portion of the case and the participating staff, including nursing and anesthesiology staff, should be oriented in advance. Before the patient enters the room, a gel pad/beanbag is placed on the operating table to avoid patient slippage during extreme tilt. The patient is placed on the pad and induced/intubated by anesthesiology. Lines and tubes are inserted, including any necessary arterial or venous catheters, an orogastric tube, a Foley catheter and, when relevant (as discussed earlier), ureteral stents. The legs are wrapped with knee-length sequential compression device sleeves and placed in Allen stirrups for modified lithotomy positioning, with extra padding inserted behind the leg. Both arms are secured at the sides by placing the beanbag to suction, and gauze padding is used to protect the skin from any lines or tubing. Foam and tape are placed across the chest to secure the upper body to the bed and shoulder rests are placed on a padded support that is secured to the table.