Demonstrations of the Overstitch endoscopic suturing device including (a) the Olympus double channel therapeutic gastroscope with needle driver attached, (b) OverStitch system with handle and needle driver (needle anchor not shown), (c) working ends of the device with components labeled, (d) polypropylene and polydioxanone suture, (e) suture cinch device, (f) distal end of tissue helix device, and (g) overtube demonstrating specialized end inflation catheter both designed to retain gas insufflation. (Used with permission from Apollo Endosurgery)
Patient and Procedure Preparation
Frequently, endoscopic suturing procedures are performed under general anesthesia given the complexity of the related procedures, and the large caliber of devices passed per os along the esophagus. Beyond improving patient tolerance, endotracheal intubation secures the airway and allows for supine positioning with fear of pulmonary aspiration if desired for adjunct fluoroscopy. If supine position is utilized, the endoscopist will need to appreciate the possibility of decreased device response due to angulation and restriction of the tension cable. It is recommended to perform a diagnostic endoscopy to assess the area of interest and ensure the pre-procedure plan of action remains appropriate and feasible. If a foregut procedure is being performed, during this assessment, the overtube may be positioned by loading the device over the proximal end of the insertion tube, passage of the distal end into the stomach, and then careful advancement of the overtube along the insertion tube until such point as the bulbous proximal end abuts the bite block. Care should be taken to cease passage if resistance is experienced as this rarely may indicate invagination of the esophageal wall between the overtube and insertion tube, which may then result in esophageal perforation. This device also incorporates a catheter through which air may be inserted to inflate a proximal circumferential balloon designed to assist in maintaining insufflation. Moreover, the catheter may be affixed to the bite block with a hemostat or similar device to prevent outward migration with movement of the endoscope.
Suture Device Equipment Set- Up
General Endoscopic Suturing Technique
Step 1: Carefully advance the dual channel therapeutic gastroscope with attached OverStitch device with the arm in closed position per os, with or without overtube, or per rectum into range of the targeted tissues of the foregut, midgut, or hindgut. With the endoscope in range, begin to plan the methods needed to achieve the desired outcome. This includes identifying what is to be apposed, the type of stitch pattern, and the sequence of sutures. For instance, the location of the first bite may in large part be determined by the decision of suture pattern and particulars of positioning. Importantly, given the nuance of over-under-under-over suture technique found with most patterns, the first bite usually involves the distal edge to be approximated, while the second is the proximal, as this will naturally allow this sequence. As the suture is loaded on the needle arm, the driver handle may then be opened to ready for the first bite. Meanwhile, the exchange catheter remains within the 3.7 mm working channel ready to recapture the suture as below (Fig. 25.3).
Step 2: While it is possible to position the needle guard and body appropriately to obtain a full thickness bite, it is recommended to utilize the tissue helix assist device to allow full control of the manipulated tissue. To do so, the device is passed through the secondary 2.8 mm leftward working channel of the therapeutic gastroscope with the distal metal spiral contained within the catheter; this may involve pulling back the blue cross on the proximal end of the device. With the helix catheter visualized endoscopically, the assistant exposes the metal spiral by pushing on the blue cross (Fig. 25.4).
Step 3: The helix is then advanced onto the tissue target, and the assistant begins to turn the blue cross clockwise 3–4 times, while the endoscopist pushes the catheter toward the tissue (Fig. 25.5). Frequently, though not always, the endoscopist will appreciate a subtle tissue bounce, and this will help ensure full thickness suturing.
Step 4: The helix catheter is then slightly withdrawn pulling the grasped tissue toward the tip of the endoscope into path of the loaded needle arum. The endoscopist may or may not slightly push forward the insertion tube or even use suction to improve alignment of the target (Fig. 25.6).
Steps 5 and 6: Next, with the tissue well within the alignment with the arm, the operator closes the needle driver handle to advance the anchor and suture though the tissues held by the helix. Without delay the anchor exchange is advanced forward to come in contact with the suture on the needle arm. As previous, a tactile click will usually, though not always, be appreciated suggesting appropriate engagement of the anchor exchanger with the suture on the needle arm (Fig. 25.7). Of importance, the suture has not yet been exchanged, and the helix remains connected with the tissue.
Step 7: Without pressing the blue button of the exchanger, gently pull the anchor exchange back to disengage the suture from the needle arm (Fig. 25.8). Again the helix remains engaged with tissues until the next step.
Step 8: The assistant next turns the helix counter clockwise a minimum of 4 rotations to release the tissue, again frequently associated with a subtle tissue bounce. The entire helix spiral should be visualized endoscopically and the catheter withdrawn slightly toward the endoscope. The assistant should then pull back on the blue cross to retract the helix, and the catheter may then be withdrawn entirely into the working channel.
Step 9: While both the sharp end of the suture is detached from the needle body and the helix from the tissue, the tissue remains engaged with the needle body until it is placed into the open position using the handle. However, in the open position, the endoscopist attempts to create some distance from the target area using the slack created while initially loading the suture with the exchanger (Fig. 25.9).
Step 10: With the first full thickness bite completed, the endoscopist next passes the suture back to the needle body to allow the process to continue. Each step above is repeated to achieve the desired suture throw.
Steps 1b–10b: The above steps are then repeated taking various bites of tissue appropriate for the chosen suture technique, be it interrupted, running, purse-string, or horizontal mattress (as described below), and the desired outcome achieved (Fig. 25.10).