16 The Uterus/Fallopian Tubes/Ovaries
Anatomy
▪Anatomy of the Uterus General Facts
General Facts
pear shaped
weight 30–120g, length 7–9cmlong (nullipara: 6–8cm)
Function
Defends against organisms invading the uterine cavity and the abdominal space.
Ensures the passage of sperm.
Contains and nourishes the embryo.
Expels the fetus during childbirth.
Form
vaginal portion
cervix
body
fundus
isthmus
Location
Flexion = inclination between longitudinal axis of the cervix and body of the uterus
Normal: anteflexion (axis of the body is almost horizontal when the woman is standing, cervical axis is pointing dorsocaudally)
Version = inclination of the cervical axis to the longitudinal axis
Normal: anteversion (cervical axis is tipped forward)
Position = position of the vaginal portion in the pelvic space
Normal: vagina at the height of the interspinal line in the center of the pelvis or slightly to the left
Factors Affecting the Location
condition of the uterine support structure
degree of fullness in the urinary bladder and rectum
processes of shrinking and displacement in the lesser pelvis
Projection onto the Wall of the Torso
lower third of the uterus: immediately above the symphysis
supravaginal part of the cervix: sacrococcygeal joint
Topographic Relationships
peritoneum
urinary bladder
rectum
vagina
small intestinal loops
sigmoid colon
fallopian tube
ovary
ureter
uterine artery and vein
Attachments/Suspensions
pelvic floor (levator ani)
suspensory ligament of the ovary-proper ligament of the ovary-round ligament of the uterus
broad ligaments/plica lata
sacrouterine and rectouterine ligaments
vesicouterine ligament
Circulation
Arterial
Uterine artery (from the internal iliac artery) anastomosed with the ovarian artery (from the aorta).
Venous
Uterine vein and diverse plexus that run into the internal iliac vein.
Lymph Drainage
lumbar lymph nodes
superficial inguinal lymph nodes
external iliac lymph nodes
obturator lymph nodes
Innervation
sympathetic nervous system from T10 to L2 via the splanchnic nerves to the celiac/superior and inferior mesenteric ganglions and renal plexus
With vessels (ovarian artery) or as independent nerve fibers, the nerves run to the hypogastric and uterovaginal plexus.
Postganglionic supply from the four sacral ganglions and the ganglion impar is under discussion.
Sacral parasympathetic nervous system (S2-S4) to the inferior hypogastric plexus and uterovaginal plexus
▪Anatomy of the Ovaries
General Facts
Size: 4cm long, 2cm wide, 1cm thick.
Weight: 6-8g.
Function
The ovaries are the female sex glands. In addition, they produce estrogens, progestogens, and steroids.
Location
In the standing female, the ovaries lie on top of the broad ligament (posterior) and between the suspensory ligament of the ovary and the proper ligament of the ovary in an infolding of peritoneum.
The longitudinal axis runs virtually craniocaudal.
The ovary sits higher in nulliparas than in multiparas. It lies in a depression (ovarian fossa) with borders formed by the following structures:
obturator internus (lateral)
external iliac vein (anterior)
umbilical artery, obturator artery, obturator nerve (caudal)
ureter, internal iliac vessels (cranioposterior)
Topographic Relationships
ovarian fossa
peritoneum
psoas fascia (via the insertion of the suspensory ligament of the ovary)
ileum
ovarian vessels
uterine artery
cecum (right ovary)
appendix (right ovary)
piriformis (in multiparas)
obturator nerve
Projection onto the Wall of the Torso
The ovaries project onto the abdominal wall in a line on the anterosuperior iliac spine (ASIS)–upper edge of the symphysis, slightly medial to the edge of the psoas.
Attachments/Suspensions
Suspensory ligament of the ovary (from ovary to ileum and psoas fascia): this ligament leads the ovarian vessels and nerves to the ovary.
Proper ligament of the ovary (from ovary to angle of the tube): it contains a branch of the uterine artery.
Peritoneal cover with mesovarium: it also covers the two upper ligaments.
Circulation
Arterial
uterine artery (from the internal iliac artery)
ovarian artery (aorta)
Venous
ovarian vein: on the right drains into the inferior vena cava; on the left drains into the left renal vein and then
inferior vena cava
uterine vein and diverse plexus that run into the internal iliac vein
Lymph Drainage
Lumbar lymph nodes.
Innervation
sympathetically, the ovaries are supplied by the same segments as the uterus.
vagus nerve
Movement Physiology according to Barral
Mobility
The uterus is highly mobile, its position dependent on the menstrual cycle, the state of fullness in the urinary bladder and rectum, and the position of the small intestinal loops.
Filled Urinary Bladder
The uterus is pressed posteriorly.
Filled Rectum
The uterus is pressed anteriorly.
Filled Rectum and Urinary Bladder
The uterus is pressed superiorly.
Pregnancy
The uterus is pressed inferiorly.
Lateral displacement occurs as the result of scarring.
The fallopian tubes are also very mobile: the fimbriae perform rhythmic movements in three planes at the start of ovulation.
To transport the oocyte, we see both segmental and peristaltic contractions of the entire fallopian tube as well as movements of the fimbriae and cilia in the tube.
The position of the ovary depends on the movements of the uterus.
Motility
Uterus
Similar to the urinary bladder: during the expiratory phase, we see a movement posterosuperiorly; during the inspiratory phase the movement is in the opposite direction.
Ovary
Left ovary: rotation in a clockwise direction and slightly superior.
Right ovary: rotation in a counterclockwise direction and slightly superior.
Physiology
The reproductive hormones are subject to a hormonal regulatory circuit with the hypothalamus, hypophysis, and ovaries serving as hormonal glands.
Hypothalamus
The hypothalamus produces luteinizing hormone (LH)-releasing hormone (LHRH), which stimulates the adenohypophysis to produce and release gonadotropic hormones.
Hypophysis
Follicle-Stimulating Hormone
The follicle-stimulating hormone (FSH) has the following effects in the ovary:
maturation of the follicles
formation of estradiol receptors.
production of estradiol from testosterone (in the testicles, it stimulates spermatogenesis)
Luteinizing Hormone
The luteinizing hormone (LH) has the following effects in the ovary:
production of estrogen and progesterone
changes in the follicular wall that lead to ovulation (in the testicles, it stimulates testosterone synthesis)
Human chorionic gonadotropin (hCG) in the placenta roughly corresponds to LH.
Hormones of the Ovaries
Estrogens
Most estrogens are formed in the ovary. The starting molecule is cholesterol, which through several intermediary steps is transformed into testosterone. This is then turned into estradiol in yet another conversion. Estrogens are also produced in other tissues from androgens (see below), and they are also formed in the testicles.
The phase of estrogen production coincides with the phase of follicular maturation.
The effect is as follows:
stimulates growth of the female reproductive organs
regeneration and growth of the endometrium
secretion of thin, spinnable, clear, alkaline mucus (facilitates the inflow of sperm)
promotes the movement of the fallopian tubes and their production of secretions
epithelial growth in the vagina; also partially responsible for a normal vaginal environment
stimulates the growth of the mammary glands
formation of subcutaneous fat deposits (female body shape)
promotes formation of secondary sexual characteristics (growth of pubic hair, pigmentation of the nipples and vulva)
lifts the mood
Progesterone
This is formed only in the ovaries and placenta from cholesterol. Progesterone production occurs during the luteal phase.
The effect is as follows:
transforms the endometrium which is proliferating under the influence of estrogen
production of thick cervical mucus that is impermeable to sperm
epithelial cells in the vagina are discharged repeatedly
lowers tonicity in the uterine muscles and reduces uterine contractions–immobilizes the uterus during pregnancy
under the influence of progesterone, we see a general drop in tonicity of the smooth muscles
stimulates the growth of the mammary glands
progesterone causes a rise in body temperature of 0.4-0.6°C
In conclusion, we can say that estrogens prepare the body for conception and progesterone prepares it for pregnancy.